{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:20Z","timestamp":1753870160876,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T00:00:00Z","timestamp":1706054400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A young woman with historically mild asthma experienced worsening breathlessness and cough with competitive ice skating. Despite optimizing and escalating treatment for her eosinophilic asthma, and addressing known exacerbating factors, her symptoms remained uncontrolled and refractory to bronchodilators and oral corticosteroids. Objective testing suggested her presentation was out of keeping with asthma alone, and she was suspected to have comorbid dysfunctional breathing and\/or inducible laryngeal obstruction. Evidence was required to confirm the diagnoses, assess each condition's contribution to her symptom burden, and guide therapy. As exercise was a predominant trigger, she proceeded to cardiopulmonary exercise test with continuous laryngoscopy during exercise (CPET\u2010CLE). Testing confirmed the presence of two forms of inducible laryngeal obstruction and evidence of hyperventilation predominant dysfunctional breathing. This case highlights the importance of identifying coexisting conditions in difficult\u2010to\u2010treat asthma, and the value of structured multidisciplinary assessment in referral centres for such individuals.<\/jats:p>","DOI":"10.1002\/rcr2.1282","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T00:21:05Z","timestamp":1706142065000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Untangling asthma, inducible laryngeal obstruction, and dysfunctional breathing in a competitive sportsperson"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0094-7715","authenticated-orcid":false,"given":"Alice L.","family":"Crawford","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"Medical School Curtin University  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5340-0329","authenticated-orcid":false,"given":"Niranjan","family":"Setty","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brooke","family":"Kyle","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Baumwol","sequence":"additional","affiliation":[{"name":"Department of Speech Pathology Sir Charles Gairdner Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John D.","family":"Blakey","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"Medical School Curtin University  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,24]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_2_1","DOI":"10.5694\/mja14.01564"},{"volume-title":"Global Strategy for Asthma Management and Prevention,","year":"2023","author":"Global Initiative for Asthma.","key":"e_1_2_8_3_1"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.1111\/j.1440-1843.2009.01568.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.5603\/ARM.2020.0087"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.1183\/16000617.0088-2015"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.1111\/resp.13134"},{"issue":"1","key":"e_1_2_8_8_1","first-page":"1","article-title":"British guideline on the management of asthma","volume":"69","year":"2014","journal-title":"Thorax"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_1","DOI":"10.1183\/09031936.00202013"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.1016\/j.anai.2014.08.009"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1016\/j.jaci.2019.12.906"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_1","DOI":"10.1080\/17476348.2017.1335602"},{"doi-asserted-by":"publisher","key":"e_1_2_8_13_1","DOI":"10.1111\/resp.14147"},{"doi-asserted-by":"publisher","key":"e_1_2_8_14_1","DOI":"10.1183\/13993003.02221-2016"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,26]],"date-time":"2024-01-26T11:19:07Z","timestamp":1706267947000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/rcr2.1282"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1282","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-12-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01282"}}