{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:22Z","timestamp":1753870162949,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T00:00:00Z","timestamp":1711324800000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Multiple myeloma (MM) is characterized by neoplastic proliferation of monoclonal antibody producing plasma cells. In clinical practice, pleural effusion is seen in up to 6% of MM patients, with many causative factors. Nevertheless, true myelomatous pleural effusion, defined as infiltration of the pleura by myeloma cells, is very rare. In this case report, we present two patients with biopsy proven myelomatous pleural effusion. The first patient developed myelomatous pleural effusion as initial presentation while the second patient's pleural effusion occurred during disease relapse. In both cases, prompt diagnosis via medical thoracoscopy (MT) followed by early commencement of myeloma specific chemotherapy led to clinical, biochemical, and radiological resolution and therefore were crucial steps in the management of myelomatous pleural effusion.<\/jats:p>","DOI":"10.1002\/rcr2.1333","type":"journal-article","created":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T23:59:24Z","timestamp":1711411164000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Utilizing medical thoracoscopy for the diagnosis of myelomatous pleural effusion: 2 case reports"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9868-1398","authenticated-orcid":false,"given":"Khai Lip","family":"Ng","sequence":"first","affiliation":[{"name":"Department of Medicine Melaka Hospital  Melaka Malaysia"},{"name":"Department of Pulmonology Serdang Hospital  Kajang Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3220-3876","authenticated-orcid":false,"given":"Sin Nee","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pulmonology Serdang Hospital  Kajang Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2671-4189","authenticated-orcid":false,"given":"Nai\u2010Chien","family":"Huan","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Queen Elizabeth Hospital  Kota Kinabalu Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona Zaria","family":"Nasaruddin","sequence":"additional","affiliation":[{"name":"Department of Pulmonology Serdang Hospital  Kajang Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriah","family":"Othman","sequence":"additional","affiliation":[{"name":"Department of Pathology Serdang Hospital  Kajang 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