{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:31:11Z","timestamp":1787679071263,"version":"build-2784847793"},"reference-count":7,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Cryptococcus<\/jats:italic> is a yeast\u2010like fungus. Pulmonary lesions caused by <jats:italic>Cryptococcus neoformans<\/jats:italic> typically present as single or multiple nodules or infiltrative lesions in the lungs; however, endobronchial lesions are rare. A 40\u2010year\u2010old previously healthy Japanese man was referred to our hospital due to an abnormality detected on chest computed tomography. The analysis revealed focal bronchiectasis and bronchial wall thickening in the right upper lobe, which persisted for 6\u2009months. Bronchoscopy showed reddish and edematous mucosa, stenosed bronchi (right B1 and B3), and white moss at the bifurcation of the right upper bronchus. Transbronchial biopsy revealed numerous yeast\u2010like fungi and an encapsulated body. Bronchial washing for fungus culture identified <jats:italic>Cryptococcus neoformans.<\/jats:italic> Although analysis for serum cryptococcal antigen was negative, bronchoscopy led to a definitive diagnosis. Antifungal treatment improved the bronchial wall thickening. This is a rare case of endobronchial cryptococcosis caused by <jats:italic>Cryptococcus neoformans<\/jats:italic> without pulmonary parenchymal involvement in an immunocompetent host.<\/jats:p>","DOI":"10.1002\/rcr2.1343","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T23:59:25Z","timestamp":1712188765000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endobronchial cryptococcosis without pulmonary parenchymal involvement caused by <i>Cryptococcus neoformans<\/i> in an immunocompetent host"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9662-2609","authenticated-orcid":false,"given":"Yui","family":"Shimanuki","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noboru","family":"Iizuka","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shion","family":"Miyoshi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Sonobe","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naobumi","family":"Tochigi","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuma","family":"Kishi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200205000-00002"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-022-01805-y"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.53.1616"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcr2.1245"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.6559-20"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10156-008-0617-0"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2018.09.014"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T03:35:07Z","timestamp":1714016107000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1002\/rcr2.1343"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1343","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2024-01-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01343"}}