{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T05:09:05Z","timestamp":1768972145370,"version":"3.49.0"},"reference-count":6,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This case report describes a 78\u2010year\u2010old man initially treated for pneumonia and lung abscess who was resistant to antimicrobial treatment and was eventually diagnosed with ciliated adenocarcinoma. Ciliated adenocarcinoma, a rare non\u2010terminal respiratory unit (TRU)\u2010type lung adenocarcinoma, presents a unique diagnostic challenge because of its similarity to pneumonia and lung abscesses. Morphologically, the ciliated adenocarcinoma in this case appeared to be a non\u2010TRU type adenocarcinoma, with partial mucous epithelium, no visible extracellular mucus, thyroid transcription factor (TTF)\u20101 negativity, and mucin (MUC) 5AC positivity on immunostaining. The patient was considered to have ciliated adenocarcinoma based on the fact that the mucous epithelium was partial and extracellular mucus was not prominent. This case emphasizes the importance of considering malignancy in patients with non\u2010resolving pulmonary infections.<\/jats:p>","DOI":"10.1002\/rcr2.1407","type":"journal-article","created":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:09:59Z","timestamp":1718064599000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A ciliated adenocarcinoma of the lung mimicking lung abscess and pneumonia"],"prefix":"10.1002","volume":"12","author":[{"given":"Naoki","family":"Fujimoto","sequence":"first","affiliation":[{"name":"Division of Respiratory Medicine, Center for Respiratory Diseases National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6902-9085","authenticated-orcid":false,"given":"Kohei","family":"Fujita","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Center for Respiratory Diseases National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayami","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koki","family":"Moriyoshi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiminobu","family":"Tanizawa","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Center for Respiratory Diseases National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.76"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200206000-00010"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12693"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2014.03.013"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-16953"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmedc.2011.05.001"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T09:31:32Z","timestamp":1719307892000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":6,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/rcr2.1407"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1407","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"2024-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01407"}}