{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T20:08:38Z","timestamp":1777838918713,"version":"3.51.4"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T00:00:00Z","timestamp":1451433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 67\u2010year\u2010old man with a history of asbestos exposure and rounded atelectasis complained of cough and swelling in the left submandibular region. Computed tomography showed an increase in size of the right lower lung lobe lesion, which was recognized as the pre\u2010existing rounded atelectasis, as well as swelling of the pancreas and submandibular glands. Biopsy from a submandibular gland and the pulmonary lesion led to a diagnosis of immunoglobulin <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>4\u2010related disease (<jats:styled-content style=\"fixed-case\">IgG4\u2010RD<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">IgG4\u2010RD<\/jats:styled-content> is a recently recognized disease that was first reported as an autoimmune disease; however, some reports have indicated another pathogenesis of an allergic nature that is characterized by type 2 helper <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content> cell (<jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>h2) inflammation. Additionally, it is recognized that long\u2010term exposure to asbestos can cause immune dysregulation. Here we present a case of <jats:styled-content style=\"fixed-case\">IgG4\u2010RD<\/jats:styled-content> associated with asbestos\u2010related pleural disease. Asbestos\u2010induced immune dysregulation may be one etiology of <jats:styled-content style=\"fixed-case\">IgG4\u2010RD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1002\/rcr2.142","type":"journal-article","created":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T08:56:37Z","timestamp":1451465797000},"page":"22-24","source":"Crossref","is-referenced-by-count":15,"title":["<scp>IgG<\/scp>4\u2010related disease in asbestos\u2010related pleural disease"],"prefix":"10.1002","volume":"4","author":[{"given":"Yasutaka","family":"Onishi","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine National Hospital Organization Himeji Medical Center  Himeji City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuharu","family":"Nakahara","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Hospital Organization Himeji Medical Center  Himeji City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuya","family":"Hirano","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Hospital Organization Himeji Medical Center  Himeji City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Hospital Organization Himeji Medical Center  Himeji City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuji","family":"Kawamura","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Hospital Organization Himeji Medical Center  Himeji City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiro","family":"Mochiduki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Hospital Organization Himeji Medical Center  Himeji City Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,12,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2013.236"},{"key":"e_1_2_6_3_1","first-page":"261","article-title":"Immunological effects of silica and asbestos","volume":"4","author":"Otsuki T","year":"2007","journal-title":"Cell. 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