{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:28Z","timestamp":1753870168450,"version":"3.41.2"},"reference-count":6,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"Abstract<\/jats:title>Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory disease induced by exaggerated immune responses to Aspergillus<\/jats:italic> species. Although ABPA has a high recurrence (48%), its instances with sequential isolation of distinct Aspergillus<\/jats:italic> species are sporadic. Only one case report has documented the metachronous isolation of Aspergillus fumigatus<\/jats:italic> and Aspergillus flavus<\/jats:italic>. However, no reported cases of metachronous isolation involving three distinct Aspergillus<\/jats:italic> species exist. Herein, we report a novel case of a 47\u2010year\u2010old Japanese man with sequential metachronous isolation of A. flavus<\/jats:italic>, A. terreus<\/jats:italic>, and A. fumigatus<\/jats:italic>. Initially presenting with symptoms of productive cough and pulmonary infiltration, the patient experienced two relapses following treatment with oral prednisolone. Adjustments in therapy, including voriconazole and a tailored corticosteroid regimen, resulted in significant improvement without relapse for over 6 months. This case report highlights the challenges and successful management of ABPA involving multiple Aspergillus<\/jats:italic> species.<\/jats:p>","DOI":"10.1002\/rcr2.1423","type":"journal-article","created":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:21:30Z","timestamp":1720052490000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Allergic bronchopulmonary aspergillosis with metachronous isolation of three distinct Aspergillus<\/i> species"],"prefix":"10.1002","volume":"12","author":[{"given":"Yosuke","family":"Sasahara","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine Kitakyushu General Hospital Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5587-1899","authenticated-orcid":false,"given":"Kentaro","family":"Akata","sequence":"additional","affiliation":[{"name":"Division of Infection Control and Prevention University of Occupational and Environmental Health, Japan Kitakyushu Japan"},{"name":"Department of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1876-3287","authenticated-orcid":false,"given":"Kei","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Orihashi","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Kitakyushu General Hospital Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Yatera","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine University of Occupational and Environmental Health, Japan Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.08.029"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2017.04.011"},{"key":"e_1_2_9_4_1","first-page":"1099","article-title":"Development of infection with aspergillus flavus in woman being treated for allergic pulmonary Aspergillosis caused by aspergillus fumigatus (in Japanese)","volume":"10","author":"Yamamoto K","year":"1995","journal-title":"Nihon Kyobu Shikkan Gakkai Zasshi"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/13693786.2010.548084"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.08.007"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mycmed.2023.101392"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1423","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T02:56:30Z","timestamp":1721962590000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":6,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/rcr2.1423"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1423","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01423"}}