{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:13:18Z","timestamp":1790611998613,"version":"4.1.0"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T00:00:00Z","timestamp":1467590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2016,9]]},"abstract":"Idiopathic pulmonary haemosiderosis (IPH<\/jats:styled-content>) is a rare cause of diffuse alveolar haemorrhage during childhood, and its precise pathophysiology and long\u2010term clinical course remain unclear. A 31\u2010year\u2010old man was diagnosed with IPH<\/jats:styled-content> at four years of age and had recurrent episodes of haemoptysis. The patient's symptoms responded well to steroids. However, pulmonary fibrosis and the cystic region in the lung progressively worsened. At age 27, the patient developed polyarthritis with positive anti\u2010cyclic citrullinated peptide antibodies. The patient also developed hand synovitis, which was diagnosed with ultrasonography. These results indicate complications from rheumatoid arthritis. The patient's dyspnoea gradually worsened, and at the age of 31, he developed pneumothorax and an acute exacerbation of IPH<\/jats:styled-content>. The clinical course from ages 4 to 31 included progressive chronic respiratory failure because of pulmonary fibrosis, acute exacerbations, complications with rheumatoid arthritis, and deliberation regarding lung transplantation. The development of rheumatoid arthritis after the onset of IPH<\/jats:styled-content> supports the theory of an autoimmune mechanism of IPH<\/jats:styled-content>.<\/jats:p>","DOI":"10.1002\/rcr2.174","type":"journal-article","created":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T09:22:44Z","timestamp":1467624164000},"source":"Crossref","is-referenced-by-count":3,"title":["Long\u2010term clinical course of idiopathic pulmonary haemosiderosis with rheumatoid arthritis"],"prefix":"10.1002","volume":"4","author":[{"given":"Shunsuke","family":"Sugimoto","sequence":"first","affiliation":[{"name":"Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiro","family":"Terada","sequence":"additional","affiliation":[{"name":"Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Naito","sequence":"additional","affiliation":[{"name":"Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rintaro","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Tsushima","sequence":"additional","affiliation":[{"name":"Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Tatsumi","sequence":"additional","affiliation":[{"name":"Department of Respirology, Graduate School of Medicine Chiba University Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1984.tb09978.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-8-161"},{"key":"e_1_2_5_4_1","first-page":"333","article-title":"Idiopathic pulmonary hemosiderosis: clinical profile and follow up of 26 children","volume":"44","author":"Kabra SK","year":"2007","journal-title":"Indian Pediatr."},{"key":"e_1_2_5_5_1","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1183\/09031936.94.07051009","article-title":"Bronchoalveolar lavage findings in a young adult with idiopathic pulmonary haemosiderosis and coeliac disease","volume":"7","author":"Bouros D","year":"1994","journal-title":"Eur. 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