{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T12:38:54Z","timestamp":1771677534571,"version":"3.50.1"},"reference-count":5,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,9,25]],"date-time":"2016-09-25T00:00:00Z","timestamp":1474761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p>A 31\u2010year\u2010old woman presented with a 2\u2010month history of dull left back pain. Chest roentgenography revealed pleural thickening in the left lung apex, whereas chest computed tomography showed a left pleural effusion with diffuse pleural thickening. Based on these findings, malignant mesothelioma was suspected. Video\u2010assisted thoracoscopic pleural biopsy was performed, and subsequent staining of the specimen revealed negative results for anti\u2010cytokeratin antibodies and positive results for vascular endothelial immunohistochemical markers. Therefore, a diagnosis of epithelioid hemangioendothelioma (<jats:styled-content style=\"fixed-case\">EHE<\/jats:styled-content>) was made, and chemotherapy with carboplatin, pemetrexed, and bevacizumab was initiated. After the fourth course of treatment, the disease was well controlled with a 90% reduction of the left pleural effusion. This case is very rare in that the <jats:styled-content style=\"fixed-case\">EHE<\/jats:styled-content> originated from the pleura. Additionally, there has been no report of pemetrexed for treatment of <jats:styled-content style=\"fixed-case\">EHE<\/jats:styled-content>.<\/jats:p>","DOI":"10.1002\/rcr2.191","type":"journal-article","created":{"date-parts":[[2016,9,26]],"date-time":"2016-09-26T00:36:43Z","timestamp":1474850203000},"source":"Crossref","is-referenced-by-count":20,"title":["Pemetrexed for epithelioid haemangioendothelioma of the pleura"],"prefix":"10.1002","volume":"4","author":[{"given":"Shingo","family":"Kanemura","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Hyogo College of Medicine  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kozo","family":"Kuribayashi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Hyogo College of Medicine  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumiko","family":"Moriya","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Hyogo College of Medicine  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeki","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pathology Hyogo College of Medicine  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tohru","family":"Tsujimura","sequence":"additional","affiliation":[{"name":"Department of Pathology Hyogo College of Medicine  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Hyogo College of Medicine  Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,9,25]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"6a","article-title":"Intravascular bronchioloalveolar tumor","volume":"78","author":"Dail DH","year":"1975","journal-title":"Am. 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