{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:53:30Z","timestamp":1786978410755,"version":"build-2736575974"},"reference-count":7,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T00:00:00Z","timestamp":1477353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2016,11]]},"abstract":"\n Chinese traditional medicine, Nijutsuto, is used to treat patients with frozen shoulder and osteoarthritis. Herbal medicine is often linked to the development of interstitial lung disease. An 83\u2010year\u2010old Japanese man with osteoarthritis who was on Nijutsuto was admitted to our hospital with dyspnoea and severe cough after 2 weeks from initiation of Nijutsuto. A chest computed tomography scan on admission showed diffuse ground glass opacity with traction bronchiectasis. Thus, he was diagnosed with Nijutsuto\u2010induced interstitial lung disease, and was treated with a high dose of methylprednisolone and cyclophosphamide. However, the patient died of respiratory failure 2 weeks after admission. The patient was definitively diagnosed with diffuse alveolar damage by pathological autopsy. Nijutsuto contains\n Radix Scutellariae<\/jats:italic>\n , which is considered to be the cause of interstitial lung disease. Chinese traditional medicine containing\n both Radix Scutellariae and Licorice<\/jats:italic>\n should be carefully used because of its potential role in the development of diffuse alveolar damage.\n <\/jats:p>","DOI":"10.1002\/rcr2.195","type":"journal-article","created":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T09:32:40Z","timestamp":1477387960000},"source":"Crossref","is-referenced-by-count":2,"title":["Development of diffuse alveolar damage after initiation of Nijutsuto"],"prefix":"10.1002","volume":"4","author":[{"given":"Motoyasu","family":"Kato","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Juntendo University Urayasu Hospital Chiba Japan"},{"name":"Department of Respiratory Medicine Juntendo University Graduate School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Juntendo University Urayasu Hospital Chiba Japan"},{"name":"Department of Respiratory Medicine Juntendo University Graduate School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Izumi","sequence":"additional","affiliation":[{"name":"Department of Pathology Juntendo University Urayasu Hospital Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshimasa","family":"Uekusa","sequence":"additional","affiliation":[{"name":"Department of Pathology Kanto Rosai Hospital Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeru","family":"Tominaga","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Juntendo University Urayasu Hospital Chiba Japan"},{"name":"Department of Respiratory Medicine Juntendo University Graduate School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhisa","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Juntendo University Graduate School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.40.764"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2012.11.013"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.96.09122691"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.58.10.872"},{"key":"e_1_2_5_6_1","first-page":"502","volume-title":"Pathology of the lung","author":"Colby TV","year":"1988"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(13)70053-5"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2106157"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.195","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.195","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.195","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.195","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.195","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T20:03:43Z","timestamp":1696449823000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,25]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1002\/rcr2.195"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.195","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,25]]},"article-number":"e00195"}}