{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:57:13Z","timestamp":1767707833671,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p>Granulomatosis with polyangiitis (<jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content>) frequently involves the upper respiratory tracts, but involvement of the epiglottis is extremely rare. This report describes a patient initially presenting with dysphagia and increasing stridor due to epiglottitis. Bronchoscopy showed swelling of the epiglottis with partly whitish nodular lesions, with biopsy specimens showing neutrophil infiltration and necrosis. Chest computed tomography showed multiple nodular consolidations in the bilateral lung parenchyma, and histological findings were consistent with vasculitis. The patient was diagnosed with <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content> and responded well to treatment with prednisolone and cyclophosphamide. Although an uncommon manifestation, <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content> should be included in the differential diagnosis of epiglottitis, especially in patients with lung parenchymal lesions suggestive of <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content>.<\/jats:p>","DOI":"10.1002\/rcr2.226","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T12:19:05Z","timestamp":1488370745000},"source":"Crossref","is-referenced-by-count":5,"title":["Granulomatosis with polyangiitis involving the epiglottis"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6132-2810","authenticated-orcid":false,"given":"Yuya","family":"Aono","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Iwata City Hospital  Iwata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Imokawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Iwata City Hospital  Iwata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Uto","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Iwata City Hospital  Iwata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Iwata City Hospital  Iwata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumihiko","family":"Tanioka","sequence":"additional","affiliation":[{"name":"Division of Pathology Iwata City Hospital  Iwata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Suda","sequence":"additional","affiliation":[{"name":"Second Division, Department of Internal Medicine Hamamatsu University School of Medicine  Hamamatsu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(83)80011-X"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199006000-00006"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(97)90034-4"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2014.937475"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-002-1422-2"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.226","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T17:00:36Z","timestamp":1696525236000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1002\/rcr2.226"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.226","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2017,3]]},"article-number":"e00226"}}