{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:06:21Z","timestamp":1773849981894,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,26]],"date-time":"2017-03-26T00:00:00Z","timestamp":1490486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p>A 72\u2010year\u2010old Japanese woman was admitted at Saga University Hospital for fever, malaise, and productive cough. Six years ago, she had been diagnosed with bronchial asthma and was treated with inhaled corticosteroids. Chest radiograph and computed tomography on admission showed infiltrates in the right middle lobe, a mass lesion in the left lower lobe, and bronchiectasis in both lower lobes. Sputum examination showed Gram\u2010positive rods with phagocytosis by neutrophils. These bacilli were identified as <jats:italic>Nocardia otitidiscaviarum<\/jats:italic> by <jats:styled-content style=\"fixed-case\">16S<\/jats:styled-content> ribosomal <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> sequencing. Therefore, she was diagnosed with pulmonary nocardiosis and was treated with trimethoprim\/sulfamethoxazole (<jats:styled-content style=\"fixed-case\">TMP\u2013SMX<\/jats:styled-content>) and minocycline (<jats:styled-content style=\"fixed-case\">MINO<\/jats:styled-content>). However, she had to discontinue these antibiotics because of severe nausea and anorexia and instead was treated with fluoroquinolone for 6 months. There was resolution of the disease thereafter. Pulmonary nocardiosis with bronchial asthma and bronchiectasis can be successfully treated with fluoroquinolone, an alternative to <jats:styled-content style=\"fixed-case\">TMP\u2013SMX<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">MINO<\/jats:styled-content>.<\/jats:p>","DOI":"10.1002\/rcr2.229","type":"journal-article","created":{"date-parts":[[2017,3,27]],"date-time":"2017-03-27T00:02:41Z","timestamp":1490572961000},"source":"Crossref","is-referenced-by-count":12,"title":["Successful treatment of pulmonary nocardiosis with fluoroquinolone in bronchial asthma and bronchiectasis"],"prefix":"10.1002","volume":"5","author":[{"given":"Hironori","family":"Sadamatsu","sequence":"first","affiliation":[{"name":"Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine Saga University  Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0461-5072","authenticated-orcid":false,"given":"Koichiro","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine Saga University  Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Tashiro","sequence":"additional","affiliation":[{"name":"Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine Saga University  Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutoshi","family":"Komiya","sequence":"additional","affiliation":[{"name":"Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine Saga University  Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine Saga University  Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoko","family":"Sueoka\u2010Aragane","sequence":"additional","affiliation":[{"name":"Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine Saga University  Saga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,26]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2007.01078.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.10.4497-4501.2003"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2016.3755"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02950.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090724"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-0871"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2014.04.008"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resinv.2013.09.004"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.43.615"},{"key":"e_1_2_4_11_1","first-page":"537","article-title":"A case of primary pulmonary nocardiosis with multiple pulmonary nodules successfully treated with moxifloxacin","volume":"47","author":"Kitamura A","year":"2009","journal-title":"Nihon Kokyuki Gakkai Zasshi"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.229","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.229","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T17:00:40Z","timestamp":1696525240000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,26]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1002\/rcr2.229"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.229","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,26]]},"article-number":"e00229"}}