{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:35Z","timestamp":1753870175983,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,5,28]],"date-time":"2017-05-28T00:00:00Z","timestamp":1495929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>Asthma exacerbation is associated with respiratory infections, including those by viruses and atypical bacteria. We herein report a case of severe acute asthma in an adult caused by <jats:italic>Chlamydophila pneumoniae<\/jats:italic> (<jats:italic>C. pneumoniae<\/jats:italic>) infection. A 39\u2010year\u2010old woman without a history of asthma reported to the emergency department with progressive worsening of cough, shortness of breath, and wheezing with low oxygen saturation. A computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) scan revealed patchy ground\u2010glass opacity and bronchial wall thickening. She was treated with systemic corticosteroids, inhaled short\u2010acting \u03b22 agonists, aminophylline, doripenem, and levofloxacin. Through successful treatment in the intensive care unit (<jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>), her condition and the chest X\u2010ray and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> findings improved. <jats:italic>Chlamydophila pneumoniae<\/jats:italic> infection was confirmed by elevated paired serum <jats:italic>C. pneumoniae<\/jats:italic>\u2010specific <jats:styled-content style=\"fixed-case\">IgA<\/jats:styled-content> antibodies. <jats:italic>Chlamydophila pneumoniae<\/jats:italic> infection is an important cause of severe acute asthma. On <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>, findings typical of <jats:italic>C. pneumoniae<\/jats:italic> pneumonia were noted.<\/jats:p>","DOI":"10.1002\/rcr2.239","type":"journal-article","created":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T12:57:38Z","timestamp":1496149058000},"source":"Crossref","is-referenced-by-count":2,"title":["Severe acute asthma caused by <i>Chlamydophila pneumoniae<\/i> infection"],"prefix":"10.1002","volume":"5","author":[{"given":"Yoshinari","family":"Endo","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Shizuoka General Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2352-7580","authenticated-orcid":false,"given":"Toshihiro","family":"Shirai","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Shizuoka General Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Saigusa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Shizuoka General Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eisuke","family":"Mochizuki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Shizuoka General Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,28]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2010.02505.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2005.00752.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63126-2"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62992-4"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2381040088"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.239","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T18:52:04Z","timestamp":1696531924000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,28]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1002\/rcr2.239"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.239","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2017,5,28]]},"article-number":"e00239"}}