{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:20:33Z","timestamp":1767676833398,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T00:00:00Z","timestamp":1562025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>We present a case of a 34\u2010year\u2010old male who presented with syncope secondary to a large adenoid cystic carcinoma (ACC) of the distal trachea. A computed tomography and flexible bronchoscopy showed almost complete occlusion of the distal trachea. Resection with curative intent was performed, but resection margins were unfortunately not clear. The patient was subsequently offered adjuvant radiotherapy. Tracheal tumours comprise a small proportion of respiratory tract neoplasm, accounting for only about 2% of airway malignancies. Squamous cell carcinoma is the most common tracheal tumour, followed by ACC. Symptoms are usually attributable to the intraluminal component of the tumour causing an obstruction of the airway, resulting in stridor, dyspnoea, wheezing, haemoptysis, and cough. Syncope as a presenting symptom is exceedingly rare.<\/jats:p>","DOI":"10.1002\/rcr2.452","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T09:54:30Z","timestamp":1562061270000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Syncope due to tracheal adenoid cystic carcinoma"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8713-8015","authenticated-orcid":false,"given":"Eva Marianne Theresa","family":"Bots","sequence":"first","affiliation":[{"name":"Division of Pulmonology Stellenbosch University  Cape Town South Africa"},{"name":"Pulmonology Department Erasmus Medical Centre  Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham Christoffel","family":"van Wyk","sequence":"additional","affiliation":[{"name":"Division of Anatomical Pathology, National Health Laboratory Service Stellenbosch University  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques Teran","family":"Janson","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery Stellenbosch University  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riegardt","family":"Wagenaar","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery Stellenbosch University  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Paris","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology Stellenbosch University  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coenraad Frederik Nicolaas","family":"Koegelenberg","sequence":"additional","affiliation":[{"name":"Division of Pulmonology Stellenbosch University  Cape Town South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,2]]},"reference":[{"key":"e_1_2_4_2_1","article-title":"Airway compromise due to adenoid cystic carcinoma obstructing the distal trachea: a review of current management and clinical trials","author":"Charlton P","year":"2014","journal-title":"BMJ Case Rep."},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-019-1996-9"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/acs.2018.03.04"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2013.10.002"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000000"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.452","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T23:09:12Z","timestamp":1694300952000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,2]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/rcr2.452"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.452","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2019,7,2]]},"assertion":[{"value":"2019-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00452"}}