{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T08:16:40Z","timestamp":1778228200617,"version":"3.51.4"},"reference-count":13,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T00:00:00Z","timestamp":1563235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Four patients with active pulmonary tuberculosis (PTB) presenting with respiratory failure are reported here. Bronchogenic PTB, simulating an acute febrile illness or diffuse interstitial lung disease with short duration of symptoms, as a cause of acute respiratory failure is less recognized. If diagnosed and treated early, it has good prognosis. Three of the four patients presented here had an acute presentation with fever, dyspnoea, and hypoxemia with diffuse infiltrative lesions on radiography, and the other younger patient presented predominantly with lobar consolidation. These patients presenting with respiratory failure required intensive care management, and a diagnosis was made with bronchoalveolar lavage fluid and transbronchial lung biopsy. All four patients promptly received antitubercular therapy, showed clinicoradiological improvement, and were stable at 1 year follow up.<\/jats:p>","DOI":"10.1002\/rcr2.460","type":"journal-article","created":{"date-parts":[[2019,7,16]],"date-time":"2019-07-16T23:55:31Z","timestamp":1563321331000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Active pulmonary tuberculosis presenting with acute respiratory failure"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0247-3197","authenticated-orcid":false,"given":"Satish Chandra","family":"Kilaru","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Prathima Institute of Medical Sciences  Karimnagar India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudhir","family":"Prasad","sequence":"additional","affiliation":[{"name":"Internal Medicine, Pulmonology and Critical Care Medicine Global Hospitals  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hemanth","family":"Kilaru","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Prathima Institute of Medical Sciences  Karimnagar India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghavender Reddy","family":"Anneela","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Prathima Institute of Medical Sciences  Karimnagar India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashfaq","family":"Hasan","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Deccan College of Medical Sciences  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eshwar Chandra","family":"Nandury","sequence":"additional","affiliation":[{"name":"Department of Radiology Virinchi Hospitals  Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,16]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"Global tuberculosis report 2018","author":"World Health Organization","year":"2018"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199901000-00023"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198703000-00008"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.72.5.605"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/151.3_Pt_1.867"},{"key":"e_1_2_5_7_1","first-page":"376","article-title":"Corticosteroids in pulmonary tuberculosis. I. Over\u2010all results in Madison\u2010Minneapolis veterans administration hospitals steroid study","volume":"92","author":"Johnson JR","year":"1965","journal-title":"Am. Rev. Respir. Dis."},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340000849"},{"key":"e_1_2_5_9_1","first-page":"429","article-title":"Guntupalli. Predictors of development and outcome in patients with acute respiratory distress syndrome due to tuberculosis","volume":"10","author":"SK Sharma A","year":"2006","journal-title":"Int. J. Tuberc. Lung Dis."},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-102-2-164"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/11.Supplement_2.S369"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116430"},{"key":"e_1_2_5_13_1","first-page":"505","article-title":"The effect of Mycobacterium tuberculosis on the susceptibility of human cells to the stimulatory and toxic effects of tumor necrosis factor","volume":"77","author":"Filley EA","year":"1992","journal-title":"Immunology"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050333"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.460","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T23:09:26Z","timestamp":1694300966000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,16]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/rcr2.460"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.460","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,16]]},"assertion":[{"value":"2019-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00460"}}