{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:12Z","timestamp":1753870152835,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T00:00:00Z","timestamp":1573084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>Medical thoracoscopy, also called \u201clocal anesthetic thoracoscopy\u201d and \u201cpleuroscopy,\u201d is a minimally invasive single\u2010port endoscopic technique that provides direct visualization of the pleural surfaces and channels to conduct diagnostic and therapeutic procedures. However, this technique is not helpful when substantial fibrous adhesions exist. We reported the first case of intrapleural urokinase directly under medical thoracoscopy for the diagnosis of malignant pleural mesothelioma with severe multiloculated pleural effusions in 2019. This is the second report regarding the efficacy of intrapleural urokinase directly under medical thoracoscopy for the diagnosis of multiloculated pleural effusions. Urokinase\u2010induced intrapleural fibrinolysis, which removed the fibrous septa, consequently improved the field of view under endoscopy within only 10 min. Fibrinolytic effect appeared very rapidly. This technique is available for tuberculous pleurisy with severe multiloculated pleural effusion.<\/jats:p>","DOI":"10.1002\/rcr2.498","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T23:13:32Z","timestamp":1573168412000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Intrapleural urokinase directly under medical thoracoscopy for the diagnosis of tuberculous pleurisy"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7410-4289","authenticated-orcid":false,"given":"Satoshi","family":"Terashita","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Kawachi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Tajiri","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuyoshi","family":"Ikeue","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takakazu","family":"Sugita","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,7]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/OAEM.S29942"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1556-0864(15)31612-9"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000576"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.06.37"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.137018"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.498","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.498","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T16:44:01Z","timestamp":1694191441000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,7]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1002\/rcr2.498"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.498","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2019,11,7]]},"assertion":[{"value":"2019-09-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00498"}}