{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T01:41:00Z","timestamp":1778290860548,"version":"3.51.4"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,11,17]],"date-time":"2019-11-17T00:00:00Z","timestamp":1573948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>To improve diagnosis and treatment of laryngeal sarcoidosis, we present a rare case of upper airway obstruction of unclear aetiology, with life\u2010threatening complication.The patient was a 19\u2010year boy who presented with progressive severe dyspnoea for eight\u2009months. After extensive diagnostic evaluations with no conclusive diagnosis, biopsy showed non\u2010caseating granulomatous inflammation consistent with laryngeal sarcoidosis that was treated with a CO<jats:sub>2<\/jats:sub> laser attached to a microscope. The laser was also used to resect epiglottitis, false focal cords, and aryepiglottic fold completely due to supraglottic swelling with a thick oedematous epiglottis. A 1.5\u2010ms pulse\u2010duration CO<jats:sub>2<\/jats:sub> laser attached to a microscope is an effective technique of treating laryngeal sarcoidosis and preventing its hazardous complication. Beneficial effects of this method are not only an immediate improvement of the symptoms, but also this method decreases the need for long\u2010term medical therapy with its side effects or avoid tracheostomy due to upper airway obstruction.<\/jats:p>","DOI":"10.1002\/rcr2.502","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T05:30:25Z","timestamp":1574055025000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Isolated laryngeal sarcoidosis"],"prefix":"10.1002","volume":"8","author":[{"given":"Aslan","family":"Ahmadi","sequence":"first","affiliation":[{"name":"ENT and Head and Neck Research Center and Department Five Senses Health Research Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2665-3910","authenticated-orcid":false,"given":"Fatemeh","family":"Dehghani Firouzabadi","sequence":"additional","affiliation":[{"name":"ENT and Head and Neck Research Center and Department Five Senses Health Research Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3089-8627","authenticated-orcid":false,"given":"Mohammad","family":"Dehghani Firouzabadi","sequence":"additional","affiliation":[{"name":"ENT and Head and Neck Research Center and Department Five Senses Health Research Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0282-2318","authenticated-orcid":false,"given":"Maryam","family":"Roomiani","sequence":"additional","affiliation":[{"name":"ENT and Head and Neck Research Center and Department Five Senses Health Research Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,17]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071714"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcr2.118"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.112896"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0892-1997(02)00099-1"},{"key":"e_1_2_4_6_1","article-title":"Cummings","volume":"3","author":"Flint P","year":"2015","journal-title":"Otolaryngology"},{"key":"e_1_2_4_7_1","first-page":"227","article-title":"Laryngeal sarcoidosis: a case\u2010control study","volume":"31","author":"Duchemann B","year":"2014","journal-title":"Sarcoidosis Vasc. Diffuse Lung Dis."},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2007.06.026"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Frcr2.502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.502","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T16:44:05Z","timestamp":1694191445000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,17]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1002\/rcr2.502"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.502","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,17]]},"assertion":[{"value":"2019-08-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00502"}}