{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T01:48:12Z","timestamp":1771033692992,"version":"3.50.1"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,3,8]],"date-time":"2020-03-08T00:00:00Z","timestamp":1583625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:p>Diffuse alveolar haemorrhage (DAH) is a life\u2010threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81\u2010year\u2010old male subject affected by a multifactorial DAH, in which the bleeding was related to the administration of clopidogrel and warfarin, both implicated in the context of a polycythaemia. He developed a severe acute respiratory failure treated with a ventilatory support by means of a continuous positive airway pressure (C\u2010PAP) therapy. An improvement of patient's clinical conditions was observed only after clopidogrel and warfarin discontinuation.<\/jats:p>","DOI":"10.1002\/rcr2.531","type":"journal-article","created":{"date-parts":[[2020,3,8]],"date-time":"2020-03-08T08:33:53Z","timestamp":1583656433000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Severe acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7298-7084","authenticated-orcid":false,"given":"Ernesto","family":"Crisafulli","sequence":"first","affiliation":[{"name":"Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit University of Parma  Parma Italy"},{"name":"Department of Medicine, Respiratory Medicine Unit and Section of Internal Medicine University of Verona and Azienda Ospedaliera Universitaria Integrata of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Burgazzi","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit University of Parma  Parma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Majori","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Interventional Pneumology Unit University Hospital of Parma  Parma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Serra","sequence":"additional","affiliation":[{"name":"Cardiology Division, Surgery Department University Hospital of Parma  Parma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Chetta","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit University of Parma  Parma Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,8]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2084"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpradiol.2014.01.002"},{"issue":"7","key":"e_1_2_4_4_1","first-page":"535","article-title":"Diffuse alveolar hemorrhage after clopidogrel use","volume":"13","author":"Kilaru PK","year":"2001","journal-title":"J. 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