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The patient was treated successfully with early administration of immunosuppressive therapies and polymyxin <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\u2010immobilized fiber column\u2010direct hemoperfusion, and her platypnea\u2010orthodeoxia improved with resolution of the underlying parenchymal lung disease. Reports of platypnea\u2010orthodeoxia syndrome with interstitial pneumonia are extremely rare. The recognition that platypnea\u2010orthodeoxia syndrome may occur in multiple disease states, including interstitial pneumonia, is crucial to the understanding of this perplexing disorder.<\/jats:p>","DOI":"10.1002\/rcr2.59","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T07:22:58Z","timestamp":1401866578000},"page":"91-94","source":"Crossref","is-referenced-by-count":4,"title":["Reversible platypnea\u2010orthodeoxia syndrome induced by rapidly progressive interstitial pneumonia in a patient with polymyositis"],"prefix":"10.1002","volume":"2","author":[{"given":"Hideaki","family":"Yamakawa","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Division of Respiratory Medicine Jikei University School of Medicine Kashiwa Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Respiratory Medicine Jikei University School of Medicine Kashiwa Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri","family":"Baba","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Respiratory Medicine Jikei University School of Medicine Kashiwa Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Respiratory Medicine Jikei University School of Medicine Kashiwa Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masamichi","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Respiratory Medicine Jikei University School of Medicine Kashiwa Hospital  Chiba Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyoshi","family":"Kuwano","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Respiratory Medicine Jikei University School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,4]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197604222941711"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2013.852847"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.2177\/jsci.36.122"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000339872"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/136.1.170"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0954-6111(95)90015-2"},{"key":"e_1_2_6_8_1","first-page":"113","article-title":"Severe hypoxemia with orthodeoxia due to right to left shunt in idiopathic bronchiolitis obliterans organizing pneumonia","volume":"17","author":"Naccache JM","year":"2000","journal-title":"Rev. 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