{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:55:22Z","timestamp":1777388122391,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T00:00:00Z","timestamp":1593388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hiccups are common; however, hiccups caused by sarcoidosis have rarely been reported. An unusual case involving a patient with persistent hiccups possibly caused by hilar\/mediastinal lymph node enlargement due to sarcoidosis prompted us to perform a literature search. Eight case reports relating hiccups to sarcoidosis were found and in only one case were the hiccups thought to be due to thoracic lymphadenopathy (LAD). Most cases were attributed to involvement of the central nervous system (CNS) with sarcoidosis. Management of hiccups in general is unclear and only chlorpromazine is approved by the Food and Drug Administration (FDA) for treatment; multiple other pharmacological agents have been advocated mostly being ineffective. This case report describes a patient whose hiccups were likely caused by thoracic sarcoidosis. It reviews the mechanisms of hiccups, explores co\u2010morbid conditions associated with hiccups (including sarcoidosis), and provides some recommended treatments.<\/jats:p>","DOI":"10.1002\/rcr2.605","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T05:16:02Z","timestamp":1593494162000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Sarcoidosis presenting as hiccups"],"prefix":"10.1002","volume":"8","author":[{"given":"Melissa","family":"Neumann","sequence":"first","affiliation":[{"name":"Department of Medicine Northwell Health  Manhasset NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1242-6741","authenticated-orcid":false,"given":"Kevin G.","family":"Lazo","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane","family":"Stover","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,6,29]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.36.6.1024"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine1962.28.212"},{"issue":"1","key":"e_1_2_4_4_1","first-page":"78","article-title":"Intractable hiccups as a presentation of central nervous system sarcoidosis","volume":"155","author":"Connolly JP","year":"1991","journal-title":"West. 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