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A few case reports of gastritis induced by ICIs have indicated that colitis induced by cytotoxic T\u2010lymphocyte antigen\u20104 (CTLA\u20104) resembles inflammatory bowel disease (IBD) and that programmed death\u20101\/programmed death ligand\u20101 (PD\u20101\/PD\u2010L1) inhibitor can also induce the same type of colitis. We herein encountered a case of gastritis arising after 25\u2009cycles of pembrolizumab administration in which the pathological and endoscopic findings resembled those of IBD. ICIs may induce gastritis in a manner similar to the pathogenesis of IBD.<\/jats:p>","DOI":"10.1002\/rcr2.636","type":"journal-article","created":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T08:11:46Z","timestamp":1596096706000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Severe gastritis due to pembrolizumab treatment in a lung cancer patient"],"prefix":"10.1002","volume":"8","author":[{"given":"Noriko","family":"Hayama","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Koto Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Ihara","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Koto Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichirou","family":"Honma","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Koto Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukinari","family":"Itoigawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Koto Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoichi","family":"Kaira","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Comprehensive Cancer Center, International Medical Center, Saitama Medical University  Saitama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Koto Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,30]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01474"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.14740\/gr1068w"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000491862"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2018.06.022"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.13963"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.14309\/crj.2017.57"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.13118"},{"key":"e_1_2_4_9_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/rcr2.334","article-title":"Severe upper gastrointestinal disorders in pembrolizumab\u2010treated non\u2010small cell lung cancer patient","volume":"6","author":"Onuki T","year":"2018","journal-title":"Respirol. 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