{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:33:30Z","timestamp":1787765610725,"version":"build-2784847793"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The bronchopleural fistula (BPF) is a pathological passageway between the bronchus and the pleural cavity. Diagnosing and\u00a0localising BPF can be challenging, and the traditional retrograde methylene blue (MB) perfusion method may fail to identify multifocal BPFs. This article reports a novel method for locating multifocal BPFs in patients undergoing concurrent\u00a0empyema\u00a0debridement. Initially, selective endobronchial injection of MB solution is performed under bronchoscopic guidance. Subsequently, the thoracic surgeon determines the location of BPFs as the MB solution flows into the pleural cavity. This process of injecting MB within the bronchus is repeated to locate any additional BPFs until no new ones are found. We report a case where this new method was used to identify multifocal BPFs, ultimately diagnosing three BPFs' presence. Following treatment with bronchopleural fistula occlusion, no recurrence of BPFs was observed during the follow\u2010up period.<\/jats:p>","DOI":"10.1002\/rcr2.70100","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T09:09:49Z","timestamp":1737623389000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bronchoscopic\u2010Guided Selective Endobronchial Injection of Methylene Blue Solution for Localising Peripheral Bronchopleural Fistulas During Pleural Debridement in\u00a0a Post\u2010Lobectomy Patient With Bronchopleural Fistula and Empyema"],"prefix":"10.1002","volume":"13","author":[{"given":"Yi","family":"Wei","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Tongde Hospital of Zhejiang Province  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Wang","sequence":"additional","affiliation":[{"name":"Endoscopy Department Tongde Hospital of Zhejiang Province  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honglei","family":"Tao","sequence":"additional","affiliation":[{"name":"Anesthesiology Department Tongde Hospital of Zhejiang Province  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongliang","family":"He","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery Department Tongde Hospital of Zhejiang Province  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9123-8748","authenticated-orcid":false,"given":"Weihua","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Tongde Hospital of Zhejiang Province  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-22-1809"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2013.08.008"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcr2.70081"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/103.1.41"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcr2.1292"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T08:54:20Z","timestamp":1737968060000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/rcr2.70100"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70100","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70100"}}