{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T22:48:06Z","timestamp":1768517286200,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T00:00:00Z","timestamp":1739577600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 56\u2010year\u2010old man presented with right\u2010sided pleuritic chest pain and intermittent cough for 4 months, with a background history of well\u2010controlled asthma and allergic rhinitis. Chest radiographs revealed right\u2010sided pleural effusion, the fluid chemistry showed an exudate effusion with negative cytology and abundant eosinophils. Thoracoscopic pleural biopsy showed moderate lymphoplasmacytic chronic inflammation. Immunohistochemistry showed IgG4 staining up to 90 plasma cells\/hpf (&gt;\u200910% diagnostic), and the IgG4: IgG ratio was 40% (&gt;\u200940% diagnostic), confirming the diagnosis of IgG4\u2010related disease (IgG4\u2010RD). Elevated serum IgG4 level (300\u2009mg\/dL; normal range: 3\u2013201\u2009mg\/dL), further supported the diagnosis. While eosinophilic pleural effusion (EPE) accounts for 5%\u201316% of all exudative pleural effusions, IgG4\u2010related pleural disease is an extremely rare cause of EPE.<\/jats:p>","DOI":"10.1002\/rcr2.70111","type":"journal-article","created":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T12:03:51Z","timestamp":1739621031000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>IgG4<\/scp> Related Disease Presenting With Eosinophilic Pleural Effusion"],"prefix":"10.1002","volume":"13","author":[{"given":"Ancy Elsa","family":"Thomas","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine Christian Medical College Hospital  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balamugesh","family":"Thangakunam","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Christian Medical College Hospital  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Kodiatte","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Christian Medical College Hospital  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9405-8494","authenticated-orcid":false,"given":"Devasahayam Jesudas","family":"Christopher","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine Christian Medical College Hospital  Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/lungindia.lungindia_33_24"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.08.013"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000002150"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.72"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000327200"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0000000000000581"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39205"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcp.0000127902.37822.13"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010022\u201003594\u20103"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.4046\/trd.2014.76.4.179"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318172622f"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296\u2010024\u201005611\u20107"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201052847\u20106"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.12.140"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2014.29.4.599"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2017.10.005"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/injr.injr_12_20"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39132"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.54.95"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/82_2016_36"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584\u2010020\u20100500\u20107"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T06:32:42Z","timestamp":1743834762000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/rcr2.70111"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70111","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70111"}}