{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:45:47Z","timestamp":1790779547146,"version":"4.1.0"},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T00:00:00Z","timestamp":1739232000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 61\u2010year\u2010old male was brought to the Emergency Department with severe shortness of breath, a throbbing headache, sweating, nausea, vomiting and diarrhoea after the administration of an acetazolamide tablet (250\u2009mg) at a private ophthalmology clinic. On presentation, a chest X\u2010ray was performed, showing diffuse alveolar opacities bilaterally, indicating pulmonary oedema, as seen in <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> chest also. However, his echocardiogram revealed a normal ejection fraction with no signs of ischemia. He was subsequently diagnosed with non\u2010cardiogenic pulmonary oedema (<jats:styled-content style=\"fixed-case\">NCPE<\/jats:styled-content>) and was immediately started on high\u2010flow oxygen, later requiring mechanical ventilation. The patient was admitted to the Critical Care Unit with supportive treatment, including <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> fluids and antibiotics, without steroid administration. Four days later, he was extubated and subsequently discharged from the <jats:styled-content style=\"fixed-case\">ICU<\/jats:styled-content>, followed by discharge from the hospital. Our case revolves around a rare yet potentially fatal episode of <jats:styled-content style=\"fixed-case\">NCPE<\/jats:styled-content> secondary to Acetazolamide use.<\/jats:p>","DOI":"10.1002\/rcr2.70118","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T08:19:52Z","timestamp":1739261992000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Non\u2010Cardiogenic Pulmonary Oedema Provoked by Acetazolamide"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5863-4929","authenticated-orcid":false,"given":"Naser","family":"Naser","sequence":"first","affiliation":[{"name":"The Royal College of Surgeons in Ireland of Bahrain (RCSI Bahrain)  Busaiteen Bahrain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Shehabi","sequence":"additional","affiliation":[{"name":"The Royal College of Surgeons in Ireland of Bahrain (RCSI Bahrain)  Busaiteen Bahrain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Maki","sequence":"additional","affiliation":[{"name":"The Royal College of Surgeons in Ireland of Bahrain (RCSI Bahrain)  Busaiteen Bahrain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,11]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Acetazolamide: Considerations for Systemic Administration [Internet]","author":"American Academy of Ophthalmology","year":"2015"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2021.597"},{"issue":"2","key":"e_1_2_8_4_1","first-page":"177","article-title":"Acute Pulmonary Edema After a Single Oral Dose of Acetazolamide","volume":"17","author":"Vogiatzis I.","year":"2013","journal-title":"Hippokratia"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2014.01046"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajoc.2023.101827"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T06:32:35Z","timestamp":1743834755000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/rcr2.70118"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70118","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70118"}}