{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:30Z","timestamp":1753870170794,"version":"3.41.2"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T00:00:00Z","timestamp":1739404800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 62\u2010year\u2010old woman with a history of papillary thyroid carcinoma presented to our hospital with fever and cough and was diagnosed with stage IV non\u2010small cell lung carcinoma (NSCLC). One year after chemoimmunotherapy, a re\u2010biopsy of the left pleural tumour lesion was performed. Histological analysis revealed papillary thyroid carcinoma. Another biopsy was performed on the primary tumour, and the histological analysis of the primary tumour lesion confirmed NSCLC. BRAF V600E mutations were detected in both left pleural metastatic lesions of papillary thyroid carcinoma and the primary tumour of NSCLC. Dabrafenib and trametinib reduced both tumour lesions. Here, we report a rare case of concomitant BRAF V600E\u2010mutated NSCLC and pleural metastasis from papillary thyroid carcinoma.<\/jats:p>","DOI":"10.1002\/rcr2.70119","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:28:46Z","timestamp":1739492926000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Concomitant Lung Adenocarcinoma and Pleural Metastasis of Papillary Thyroid Carcinoma With <scp>BRAF V600E<\/scp> Mutation"],"prefix":"10.1002","volume":"13","author":[{"given":"Akinari","family":"Atsumi","sequence":"first","affiliation":[{"name":"Division of Pulmonary Medicine Saiseikai Central Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5719-2697","authenticated-orcid":false,"given":"Tetsuo","family":"Tani","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Saiseikai Central Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1652-1436","authenticated-orcid":false,"given":"Kota","family":"Ishioka","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Saiseikai Central Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Saiseikai Central Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhide","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Saiseikai Central Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5490-4203","authenticated-orcid":false,"given":"Saeko","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Saiseikai Central Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2022.05.014"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2015.0004"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.3600"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20955"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1749"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100004.2010.01495.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(17)30679\u20104"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00762"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2022.0115"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T06:32:24Z","timestamp":1743834744000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/rcr2.70119"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70119","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"2024-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70119"}}