{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:31Z","timestamp":1753870171905,"version":"3.41.2"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The British Thoracic Society guidelines recommend a surgical opinion in cases of prolonged air leak or failure of lung re\u2010expansion after 3\u20135\u2009days. The management of prolonged air leak in non\u2010surgical candidates often proves to be more challenging, with no expert consensus guidelines on treatment options. There is a paucity of data for the treatment of patients with a prolonged air leak in the setting of a hydropneumothorax, who are not suitable surgical candidates. We present the case of a novel treatment approach for an 89\u2010year\u2010old male with a symptomatic, large malignant pleural effusion treated initially with a routine chest tube drainage. Subsequent management was complicated by a hydropneumothorax with a persistent and large volume air leak. He was treated successfully with an autologous blood pleurodesis using an indwelling pleural catheter. Here we describe a novel management approach for persistent air\u2010leak in the setting of a malignant hydropneumothorax. Autologous blood pleurodesis via an indwelling pleural catheter appears to be a safe and effective treatment option for non\u2010surgical candidates and allows ongoing long\u2010term drainage of a malignant effusion and air leak.<\/jats:p>","DOI":"10.1002\/rcr2.70129","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T12:46:22Z","timestamp":1744029982000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Autologous Blood Pleurodesis Through an Indwelling Pleural Catheter for the Management of Prolonged Air Leak in a Malignant Hydropneumothorax"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2373-6535","authenticated-orcid":false,"given":"Vanessa","family":"Wong","sequence":"first","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health The University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Respiratory and Sleep Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sathya","family":"Balaguruswamy","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Westmead Hospital  Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bapti","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Medicine Westmead Hospital  Sydney New South Wales Australia"},{"name":"School of Medical &amp; Health Sciences Edith Cowan University  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201807\u2010495OC"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003\u20104975(96)00034\u20103"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2022-219784"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.congress\u20102019.PA3397"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.02.020"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759\u20107714.14138"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.10.122"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.166.5.8615239"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2016.07.003"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000520656"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.5535"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20102600(18)30288\u20101"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1716883"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70129","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T02:55:40Z","timestamp":1745895340000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/rcr2.70129"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70129","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-12-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70129"}}