{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T14:10:24Z","timestamp":1758723024719,"version":"3.44.0"},"reference-count":5,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>There is limited guidance on managing <jats:styled-content style=\"fixed-case\"><jats:italic>Mycobacterium abscessus<\/jats:italic><\/jats:styled-content> pulmonary disease in Myasthenia Gravis patients. Macrolides and aminoglycosides form the backbone of <jats:styled-content style=\"fixed-case\"><jats:italic>M. abscessus<\/jats:italic><\/jats:styled-content> pulmonary disease treatment but are avoided in Myasthenia Gravis patients due to the risk of precipitating myasthenic crisis. A 29\u2010year\u2010old female, with a history of anti\u2010acetylcholine receptor antibody\u2010positive Myasthenia Gravis and bronchiectasis, was diagnosed with <jats:styled-content style=\"fixed-case\"><jats:italic>M. abscessus<\/jats:italic><\/jats:styled-content> pulmonary disease. She was commenced on a macrolide\u2010based regime safely with close monitoring, pretreatment with intravenous immunoglobulin (1\u2009g\/kg),10\u2009mg prednisolone, 500\u2009mg rituximab and augmentation of the neuromuscular junction with pyridostigmine and 3,4\u2010Diaminopyridine. She was safely discharged to the hospital in the home program and achieved clinical, radiological and microbiological response.<\/jats:p>","DOI":"10.1002\/rcr2.70166","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T09:04:34Z","timestamp":1752483874000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp><i>Mycobacterium abscessus<\/i><\/scp> Pulmonary Disease in a Myasthenia Gravis Patient: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0523-0653","authenticated-orcid":false,"given":"Daisy","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Respiratory and Sleep Disorders Medicine Royal Melbourne Hospital  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven Y. C.","family":"Tong","sequence":"additional","affiliation":[{"name":"Victorian Infectious Diseases Service Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity  Melbourne Victoria Australia"},{"name":"Department of Infectious Diseases Peter Doherty Institute for Infection and Immunity, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belinda","family":"Cruse","sequence":"additional","affiliation":[{"name":"Department of Neurology Royal Melbourne Hospital  Melbourne Victoria Australia"},{"name":"Department of Medicine Royal Melbourne Hospital, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasha P.","family":"Singh","sequence":"additional","affiliation":[{"name":"Victorian Infectious Diseases Service Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity  Melbourne Victoria Australia"},{"name":"Department of Infectious Diseases Peter Doherty Institute for Infection and Immunity, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin T.","family":"Denholm","sequence":"additional","affiliation":[{"name":"Victorian Infectious Diseases Service Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity  Melbourne Victoria Australia"},{"name":"Department of Infectious Diseases Peter Doherty Institute for Infection and Immunity, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Rees","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Sleep Disorders Medicine Royal Melbourne Hospital  Melbourne Victoria Australia"},{"name":"Department of Medicine Royal Melbourne Hospital, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/JCM10071537"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.07.035"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.NCL.2018.01.011"},{"issue":"2","key":"e_1_2_8_5_1","first-page":"53","article-title":"A Case of Pulmonary \n                     Mycobacterium abscessus\n                   Infection That Developed During Immunosuppressive Therapy for Myasthenia Gravis With Recurrent Thymoma","volume":"91","author":"Matsuse H.","year":"2016","journal-title":"Kekkaku"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010020\u201005136\u2010x"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:43:05Z","timestamp":1758721385000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/rcr2.70166"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70166","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2024-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70166"}}