{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T03:42:36Z","timestamp":1778038956679,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 70\u2010year\u2010old woman with sputum and cough was diagnosed with nontuberculous mycobacterial pulmonary disease based on multiple cultures of <jats:styled-content style=\"fixed-case\"><jats:italic>Mycobacterium shinjukuense<\/jats:italic><\/jats:styled-content> and computed tomography (CT) findings of bilateral nodular shadows and bronchiectasis. Treatment was initiated with ethambutol and azithromycin, and rifampicin was added 1\u2009month later. Three weeks after rifampicin therapy, she developed fever and fatigue, and CT revealed bilateral non\u2010segmental infiltrates and a reversed halo sign indicative of organising pneumonia. Rifampicin was discontinued due to suspected rifampicin\u2010induced lung injury, and a subsequent bronchial lung biopsy confirmed organising pneumonia. The patient's fever resolved with discontinuation of rifampicin, and chest imaging showed resolution of the infiltrates. Continuation with ethambutol and azithromycin did not result in fever or new shadows. We need to consider the possibility of drug\u2010induced lung injury when new shadows appear during nontuberculous mycobacterial treatment regimens.<\/jats:p>","DOI":"10.1002\/rcr2.70208","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T05:43:53Z","timestamp":1747115033000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rifampicin\u2010Induced Lung Injury in <scp><i>Mycobacterium shinjukuense<\/i><\/scp> Infection: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8341-9381","authenticated-orcid":false,"given":"Yoshimasa","family":"Hachisu","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Hanawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Hosino","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shogo","family":"Uno","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Onuki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuma","family":"Ezawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Horie","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Maebashi Red Cross Hospital  Maebashi\u2010city Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.10.013"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.025478\u20100"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.55.5460"},{"key":"e_1_2_9_5_1","article-title":"Rifampicin\u2010Induced Pneumonitis Mimicking Severe COVID\u201019 Pneumonia Infection","volume":"21","author":"Ata F.","year":"2020","journal-title":"American Journal of Medical Case Reports"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.18.0171"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.57.11.1000"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1022809"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-3088"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1125"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T11:39:13Z","timestamp":1748432353000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/rcr2.70208"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70208","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2025-03-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70208"}}