{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:37Z","timestamp":1753870177277,"version":"3.41.2"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T00:00:00Z","timestamp":1748217600000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present a patient with recurrent pneumothorax induced by lenvatinib, used for the treatment of thymic carcinoma. A 76\u2010year\u2010old Japanese man, who is a current smoker, was diagnosed with thymic carcinoma with pulmonary metastasis and pleural dissemination. Lenvatinib was initiated as third\u2010line chemotherapy in April 2022. He was subsequently admitted to our hospital in August and October 2023 for recurrent left\u2010sided pneumothorax. Following the second left pneumothorax, lenvatinib was discontinued, and he has remained free of pneumothorax for over a year. Clinicians should be aware of the potential adverse effects of lenvatinib in patients with pulmonary metastasis or pleural dissemination.<\/jats:p>","DOI":"10.1002\/rcr2.70218","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T23:58:22Z","timestamp":1748303902000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent Drug\u2010Induced Pneumothorax Associated With Lenvatinib: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"given":"Ryo","family":"Torii","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1876-3287","authenticated-orcid":false,"given":"Kei","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Ishiguro","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Shingu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryosuke","family":"Hata","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Yatera","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine University of Occupational and Environmental Health, Japan  Kitakyushu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(20)30162\u20105"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31821ea5f7"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2017.0205"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7875929"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2019.01.006"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs\u201020\u2010462"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs\u201022\u201071"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs\u201024\u2010269"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2018.11.004"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T11:38:48Z","timestamp":1748432328000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/rcr2.70218"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70218","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2025-03-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70218"}}