{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:01:01Z","timestamp":1788314461514,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The association of two rare but important congenital conditions\u2014congenital chylothorax (CCT) and congenital pulmonary airway malformation (CPAM)\u2014can be challenging to manage, especially in the absence of well\u2010established protocols. We report an association between CPAM and CCT in a newborn. After birth, CCT did not respond to conservative treatment, and at the time of CPAM resection, thoracic duct ligation and abrasive pleurodesis were also performed. Despite these interventions, the CCT persisted even with the subsequent administration of octreotide and propranolol. Finally, after 56\u2009days, chemical pleurodesis with povidone\u2010iodine was performed. Chest tube drainage ceased, and the thoracic drain was removed 4\u2009days later. Conservative treatment remains the first\u2010line approach for neonatal CCT. However, when CCT is associated with CPAM and fails to respond to conservative measures, thoracic duct ligation should be considered at the time of lung malformation resection. If these interventions remain ineffective, chemical pleurodesis is a viable therapeutic option.<\/jats:p>","DOI":"10.1002\/rcr2.70223","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T13:32:23Z","timestamp":1750080743000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Congenital Chylothorax and Congenital Pulmonary Airway Malformation: Case Report and Literature Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1118-1145","authenticated-orcid":false,"given":"Andr\u00e9a L.","family":"Corso","sequence":"first","affiliation":[{"name":"Neonatology Service\u2014Hospital de Cl\u00ednicas of Porto Alegre (HCPA)  Porto Alegre Brazil"},{"name":"Department of Pediatrics, Faculty of Medicine Federal University of Rio Grande Do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda M.","family":"Magdaleno","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine Federal University of Rio Grande Do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina R.","family":"Cappellaro","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine Federal University of Rio Grande Do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mateus M.","family":"Neves","sequence":"additional","affiliation":[{"name":"Pediatric Thoracic and Airway Surgery Unit, Pediatric Surgery Service\u2014Hospital de Cl\u00ednicas of Porto Alegre (HCPA)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ge\u00f3rgia P. F.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine Federal University of Rio Grande Do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iara R. 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