{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T22:16:57Z","timestamp":1775513817897,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Chylothorax, characterised by the accumulation of chyle in the pleural space, is a rare yet clinically significant condition. This lymphatic fluid, rich in fats absorbed from the intestine, can be caused by various factors including trauma, malignancy, and tuberculosis (TB). Traumatic causes, particularly iatrogenic procedures, account for a significant proportion of cases, followed by rare etiologies like malignancies such as lymphoma, and less commonly, tuberculosis. In the first two cases, the patient was diagnosed with tuberculosis during evaluation for chylothorax; however, in the third case, the patient developed chylothorax as a complication of mantle cell lymphoma (MCL). Two male patients, aged 43 and 45, presented with respiratory symptoms and milky pleural effusions (triglycerides &gt;\u2009180\u2009mg\/dL). In both, bronchoalveolar lavage confirmed rifampicin\u2010sensitive TB. Both patients responded to anti\u2010tubercular therapy and dietary modification. A 69\u2010year\u2010old male with a history of non\u2010Hodgkin's lymphoma developed chylothorax (triglycerides 286\u2009mg\/dL) and lymphadenopathy; imaging and biopsy confirmed MCL. He responded to chemotherapy. This series underscores the importance of considering uncommon causes of chylothorax during evaluation and tailoring treatment based on specific etiologies.<\/jats:p>","DOI":"10.1002\/rcr2.70243","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T07:00:15Z","timestamp":1752130815000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Chylothorax in Uncommon Contexts: Pulmonary Tuberculosis and Mantle Cell Lymphoma"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8882-039X","authenticated-orcid":false,"given":"Guru Prasad","family":"T J","sequence":"first","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2154-1663","authenticated-orcid":false,"given":"Athish","family":"Kannan Karur","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spurthy","family":"Padmanabha","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. R.","family":"Harshitha","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suggula Vamsi","family":"Krishna","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashmi Priya","family":"Murthy","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Olaniyan","sequence":"additional","affiliation":[{"name":"Sri Sai PC  Fort Wayne Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adewale","family":"Oyeneye","sequence":"additional","affiliation":[{"name":"Sri Sai PC  Fort Wayne Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anwadevi","family":"Arun","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franklin","family":"John","sequence":"additional","affiliation":[{"name":"Department of TB and Chest Disease Sri Devaraj Urs Academy of Higher Education and Research  Kolar Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Surgery of the Chest","author":"DeMeester T.","year":"1983"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00091-2023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-23-1636"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4065\/80.7.867"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000484694"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.114.1.154"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.rlu.0000129125.05486.c5"},{"issue":"11","key":"e_1_2_8_9_1","first-page":"700","article-title":"The Lipoprotein Profile of Chylous and Nonchylous Pleural Effusions","volume":"55","author":"Staats B. A.","year":"1980","journal-title":"Mayo Clinic Proceedings"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.4065\/84.2.129"},{"key":"e_1_2_8_11_1","volume-title":"StatPearls","author":"Lynch D. T.","year":"2023"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.6.2067"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.2.586"},{"key":"e_1_2_8_14_1","first-page":"457","article-title":"The Problem of Chylothorax","volume":"42","author":"Roy P. H.","year":"1967","journal-title":"Mayo Clinic Proceedings"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2141"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:43:04Z","timestamp":1758721384000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/rcr2.70243"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70243","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70243"}}