{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:38Z","timestamp":1753870178437,"version":"3.41.2"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present a case of a 45\u2010year\u2010old previously healthy Filipino domestic helper who presented with life\u2010threatening hemoptysis due to disseminated tuberculosis (TB) involving the larynx, tracheobronchial tree, and pulmonary parenchyma. She presented with acute respiratory distress from massive hemoptysis, necessitating emergent intubation and subsequent veno\u2010venous (V\u2010V) extracorporeal membrane oxygenation (ECMO) support. Initial chest radiography revealed bilateral upper lobe infiltrates and right middle lobe collapse. Bronchoscopic evaluation demonstrated active haemorrhage and airway obstruction secondary to clot formation. An incidental epiglottic mass was identified during laryngoscopy. Given the failure of conservative measures to control bleeding, she underwent emergent right middle and lower lobectomies. Histopathological analysis confirmed necrotizing granulomatous inflammation, and <jats:styled-content style=\"fixed-case\"><jats:italic>Mycobacterium tuberculosis<\/jats:italic><\/jats:styled-content> was detected via polymerase chain reaction (PCR) testing. She was treated with a multi\u2010drug anti\u2010tuberculosis regimen and successfully weaned from ECMO. The epiglottic mass resolved, and there was no tracheal stenosis. This case illustrates the complexities of managing tuberculosis\u2010related respiratory failure. It demonstrates the strategic role of ECMO in handling massive hemoptysis, especially in cases of concurrent laryngeal TB (LTB) and endobronchial TB (EBTB).<\/jats:p>","DOI":"10.1002\/rcr2.70244","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T09:32:27Z","timestamp":1750239147000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Catastrophic Hemoptysis in Concurrent Laryngeal and Endobronchial Tuberculosis in an Immunocompetent Host: Survival Following Brief <scp>ECMO<\/scp> Support"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6621-1459","authenticated-orcid":false,"given":"Luk Ping","family":"Lam","sequence":"first","affiliation":[{"name":"Adult Intensive Care Unit, Queen Mary Hospital  Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30308-3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0063-5"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200011000-00034"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-018-0970-y"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023770"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0126876"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(00)85010-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153450"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-020-00681-8"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12474"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.4.990"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-7-34"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.2.385"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)38908-1"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(55)90113-6"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2021.101481"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.1325"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T15:59:11Z","timestamp":1750953551000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/rcr2.70244"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70244","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70244"}}