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This case series describes three patients who were suspected to have a primary lung malignancy based on FDG\u2010PET findings, but were found to have pulmonary silicosis. With this series, we demonstrate how histologic examination can differentiate between silicosis and malignancy and provide suggestions to help clinicians differentiate between these two illnesses.<\/jats:p>","DOI":"10.1002\/rcr2.70298","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T00:28:21Z","timestamp":1753748901000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Silicosis Mimicking Lung Malignancy: A Case Series"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1768-191X","authenticated-orcid":false,"given":"Titia","family":"van Duin","sequence":"first","affiliation":[{"name":"Department of Pulmonology St. Antonius Ziekenhuis  Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Ambarus","sequence":"additional","affiliation":[{"name":"Department of Pathology St. Antonius Ziekenhuis  Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter","family":"van Es","sequence":"additional","affiliation":[{"name":"Department of Radiology St. Antonius Ziekenhuis  Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"van der Mark","sequence":"additional","affiliation":[{"name":"Department of Pulmonology St. Antonius Ziekenhuis  Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz","family":"Schramel","sequence":"additional","affiliation":[{"name":"Department of Pulmonology St. Antonius Ziekenhuis  Nieuwegein the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22084162"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-200411000-00027"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14202"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07\u20101360"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0001\u20102998(98)80038\u2010x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0051\u20102016"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31819d4778"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2019.12.003"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102012\u2010006351"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12149\u2010009\u20100309\u20106"},{"key":"e_1_2_8_12_1","first-page":"395","article-title":"Serum Biomarkers in Silicosis: Current Perspectives","volume":"40","author":"Zhang Y.","year":"2020","journal-title":"Chinese Journal of Asthma"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-023-01971-y"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010024\u201012537\u20107"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2016.04.011"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21214"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.2147\/LCTT.S156376"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70298","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T13:43:15Z","timestamp":1758721395000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/rcr2.70298"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70298","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70298"}}