{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:56:54Z","timestamp":1761659814169,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Bilateral spontaneous pneumothorax is a rare condition that occurs mainly in patients with underlying lung disease. We report the case of a 26\u2010year\u2010old Chinese male with a history of smoking who presented with sudden onset of chest tightness and dyspnoea. Chest radiography revealed bilateral pneumothoraxes, prompting the insertion of bilateral chest tubes. Further imaging with high\u2010resolution computed tomography of the chest revealed multiple bilateral, thin\u2010walled cysts with relative sparing of the lung bases and tiny peripheral nodules. The patient underwent bilateral video\u2010assisted thoracoscopic surgery with bullectomy, pleurodesis, and surgical lung biopsy. Histopathological examination revealed cysts lined by Langerhans cells with eosinophilic infiltration, establishing the diagnosis of pulmonary Langerhans cell histiocytosis (\n                    <jats:styled-content style=\"fixed-case\">PLCH<\/jats:styled-content>\n                    ). This case highlights the importance of considering cystic lung diseases, particularly\n                    <jats:styled-content style=\"fixed-case\">PLCH<\/jats:styled-content>\n                    , in young smokers presenting with spontaneous bilateral pneumothorax. Radiologic and histopathologic correlation is essential for definitive diagnosis. Smoking cessation remains the cornerstone of management.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70347","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T01:34:24Z","timestamp":1759196064000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bilateral Spontaneous Pneumothorax in a Young Gentleman"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6250-283X","authenticated-orcid":false,"given":"Albert","family":"Teng","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Singapore General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6250-2004","authenticated-orcid":false,"given":"Tzy Harn","family":"Chua","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology Singapore General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun Yuen","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology Singapore General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0559-2001","authenticated-orcid":false,"given":"Yi Hern","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine Singapore General Hospital  Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_2_1","DOI":"10.1164\/arrd.1979.120.6.1379"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_1","DOI":"10.1016\/j.chest.2016.04.026"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.3348\/kjr.2019.0057"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.1183\/09031936.06.00024004"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.1016\/j.rmed.2012.06.012"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.12998\/wjcc.v7.i14.1892"},{"doi-asserted-by":"publisher","key":"e_1_2_8_8_1","DOI":"10.1164\/rccm.201405\u20100974im"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_1","DOI":"10.4103\/0366\u20106999.182844"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.1002\/rcr2.54"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1155\/2015\/201536"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_1","DOI":"10.1183\/09031936.00210711"},{"doi-asserted-by":"publisher","key":"e_1_2_8_13_1","DOI":"10.1186\/s13023\u2010015\u20100249\u20102"},{"doi-asserted-by":"publisher","key":"e_1_2_8_14_1","DOI":"10.1183\/13993003.01017\u20102021"},{"doi-asserted-by":"publisher","key":"e_1_2_8_15_1","DOI":"10.1056\/nejmoa012087"},{"doi-asserted-by":"publisher","key":"e_1_2_8_16_1","DOI":"10.1183\/09031936.96.09102002"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:53:44Z","timestamp":1761659624000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,29]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/rcr2.70347"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70347","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,9,29]]},"assertion":[{"value":"2025-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70347"}}