{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:56:58Z","timestamp":1761659818114,"version":"build-2065373602"},"reference-count":5,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Kasabach\u2013Merritt syndrome (KMS) is a consumptive coagulopathy caused by platelet trapping due to the distinctive endothelial structure of vascular tumours. Cardiac angiosarcoma complicated by KMS is exceedingly rare. We report the case of cardiac angiosarcoma in which diffuse alveolar haemorrhage was caused by both pulmonary metastases and KMS. Invasive mechanical ventilation with high positive end\u2010expiratory pressure (PEEP) temporarily achieved transfusion\u2010independent haemostasis. However, a biopsy could not be performed during this window, and the patient experienced a fatal outcome. In case of cardiac angiosarcoma complicated by KMS, early tissue diagnosis is critical. Strategies to achieve transfusion\u2010independent haemostasis such as high PEEP may create an opportunity for prompt biopsy and facilitate timely initiation of definitive treatment.<\/jats:p>","DOI":"10.1002\/rcr2.70371","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T03:51:12Z","timestamp":1759377072000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diffuse Alveolar Haemorrhage Complicated by Pulmonary Metastasis of Cardiac Angiosarcoma and Kasabach\u2013Merritt Syndrome: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6996-407X","authenticated-orcid":false,"given":"Takuma","family":"Ikeda","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Hyogo Prefectural Amagasaki General Medical Center  Amagasaki\u2010shi Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Terada","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Hyogo Prefectural Amagasaki General Medical Center  Amagasaki\u2010shi Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Hyogo Prefectural Amagasaki General Medical Center  Amagasaki\u2010shi Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2334-2"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1179545X17699849"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000481194"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.180.6.1801671"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-024-04895-4"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70371","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:53:49Z","timestamp":1761659629000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":5,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/rcr2.70371"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70371","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-08-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70371"}}