{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:57:09Z","timestamp":1761659829761,"version":"build-2065373602"},"reference-count":6,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>IgG4\u2010related disease (IgG4\u2010RD) rarely presents as an anterior mediastinal mass and may radiologically resemble thymic neoplasms. We report a 70\u2010year\u2010old man with an incidentally detected anterior mediastinal tumour on chest CT. The lesion measured 33\u2009mm, was well\u2010circumscribed, homogeneous and partially calcified. Tumour markers and serum IgG4 were within the normal range. The patient underwent thoracoscopic resection under the diagnosis of thymoma. Histopathological examination revealed dense lymphoplasmacytic infiltration and abundant IgG4\u2010positive plasma cells, confirming IgG4\u2010related sclerosing mediastinitis. No corticosteroid therapy was administered, and the patient remained disease\u2010free over 3\u2009years of follow\u2010up. This case highlights the diagnostic challenge of mediastinal IgG4\u2010RD and the importance of considering it in the differential diagnosis of thymic tumours, even when serum IgG4 is normal.<\/jats:p>","DOI":"10.1002\/rcr2.70379","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T05:14:22Z","timestamp":1760505262000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>IgG4<\/scp>\n                    \u2010Related Sclerosing Mediastinitis Mimicking Thymoma: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8983-9239","authenticated-orcid":false,"given":"Eitetsu","family":"Koh","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery Tokyo Women's Medical University Yachiyo Medical Center  Yachiyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Sekine","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Tokyo Women's Medical University Yachiyo Medical Center  Yachiyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadao","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokyo Women's Medical University Yachiyo Medical Center  Yachiyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenzo","family":"Hiroshima","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokyo Women's Medical University Yachiyo Medical Center  Yachiyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1104650"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181f7266b"},{"issue":"6","key":"e_1_2_7_4_1","first-page":"E492","article-title":"IgG4\u2010Related Disease of the Mediastinum: A Case Mimicking Thymoma","volume":"10","author":"Sato Y.","year":"2018","journal-title":"Journal of Thoracic Disease"},{"issue":"2","key":"e_1_2_7_5_1","first-page":"304","article-title":"Development of a Clinical Diagnostic Criteria Set for IgG4\u2010Related Disease","volume":"67","author":"Carruthers M. N.","year":"2015","journal-title":"Arthritis and Rheumatology"},{"key":"e_1_2_7_6_1","unstructured":"National Comprehensive Cancer Network (NCCN) \u201cThymomas and Thymic Carcinomas Version 1.2024 \u201dPrinciples of Surgical Resection."},{"key":"e_1_2_7_7_1","unstructured":"\u201cSEOM\u2013GECP\u2013GETTHI Clinical Guideline for Thymic Epithelial Tumours \u201d2021\/2022 Update."}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:53:53Z","timestamp":1761659633000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":6,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/rcr2.70379"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70379","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-07-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70379"}}