{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:56:57Z","timestamp":1761659817018,"version":"build-2065373602"},"reference-count":5,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We report the world's first case of malignant central airway obstruction (MCAO) successfully treated with microwave ablation (MWA) under real\u2010time linear endobronchial ultrasound (EBUS) guidance. A 72\u2010year\u2010old male with stage IVB lung adenocarcinoma presented with severe dyspnea from a tumour causing 90% obstruction of the right main bronchus. Using a linear EBUS scope, we performed precise tumour mapping and positioned a MWA antenna with a 0.7\u2009cm safety margin. Controlled energy was delivered until an intratumoral temperature of 80\u00b0C was reached, achieving immediate cytoreduction. The procedure resulted in 100% luminal recanalization without requiring a stent. EBUS\u2010guided MWA is a feasible, safe, and highly effective technique for MCAO, offering unparalleled precision and thermal control. This novel approach represents a significant advancement in interventional pulmonology, enabling effective treatment of complex airway tumours while enhancing patient safety.<\/jats:p>","DOI":"10.1002\/rcr2.70384","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T06:16:48Z","timestamp":1761113808000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Linear Endobronchial Ultrasound\u2010Guided Microwave Ablation for Malignant Central Airway Obstruction: A World\u2010First Case"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7183-2646","authenticated-orcid":false,"given":"Miguel","family":"Ariza\u2010Prota","sequence":"first","affiliation":[{"name":"Pulmonology Department Hospital Universitario Central de Asturias  Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"P\u00e9rez\u2010Pallar\u00e9s","sequence":"additional","affiliation":[{"name":"Pulmonology Department Hospital HLA La Vega  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc\u00eda Garc\u00eda","family":"Alfonso","sequence":"additional","affiliation":[{"name":"Pulmonology Department Hospital Universitario Central de Asturias  Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela Lanza","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Pulmonology Department Hospital Universitario Central de Asturias  Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Garc\u00eda\u2010Clemente","sequence":"additional","affiliation":[{"name":"Pulmonology Department Hospital Universitario Central de Asturias  Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"L\u00f3pez\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Pulmonology Department Hospital Universitario Central de Asturias  Oviedo Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-1530"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00013906"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.047829"},{"issue":"4","key":"e_1_2_10_5_1","first-page":"289","article-title":"Microwave Ablation for Malignant Central Airway Obstruction: A Pilot Study","volume":"29","author":"Senitko M.","year":"2022","journal-title":"Journal of Bronchology & Interventional Pulmonology"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/acs.2018.03.08"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T13:53:47Z","timestamp":1761659627000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":5,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/rcr2.70384"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70384","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70384"}}