{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T04:42:20Z","timestamp":1764132140461,"version":"3.46.0"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Eosinophilic pneumonia (EP) often requires long\u2010term steroid treatment, which has adverse effects. We report the case of an 83\u2010year\u2010old male with minimal\u2010change nephrotic syndrome, refractory asthma and steroid\u2010induced diabetes who developed a severe steroid\u2010dependent EP relapse during steroid tapering. Considering his age, comorbidities and steroid dependency, treatment with benralizumab, an anti\u2010interleukin\u20105 receptor antibody, was initiated. Benralizumab rapidly depleted eosinophils, leading to significant clinical and radiological improvements, allowing successful sustained tapering of prednisolone to 5\u2009mg daily, and improving diabetes control without EP relapse. Benralizumab provides effective steroid\u2010sparing therapy for steroid\u2010dependent EP, particularly in complex patients.<\/jats:p>","DOI":"10.1002\/rcr2.70417","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T10:05:17Z","timestamp":1763719517000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Treatment of Steroid\u2010Dependent Severe Eosinophilic Pneumonia With Benralizumab: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"given":"Takeru","family":"Ichikawa","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine NHO Okayama Medical Center  Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0613-0423","authenticated-orcid":false,"given":"Yuki","family":"Takigawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine NHO Okayama Medical 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