{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T09:03:02Z","timestamp":1773392582492,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Silicone implants can trigger adjuvant\u2010induced autoimmune\/inflammatory syndrome (\n                    <jats:styled-content style=\"fixed-case\">ASIA<\/jats:styled-content>\n                    ). We present a 53\u2010year\u2010old woman who had undergone bilateral intramuscular silicone breast implantation at X\u221224\u2009years. Following implant rupture at X year, she developed cough, fatigue, and arthralgia, accompanied by worsening sarcoid\u2010like pulmonary lesions. After implant removal, her clinical symptoms and radiological findings improved. Histopathological examination findings identified foreign\u2010body granulomas, fulfilling diagnostic criteria for\n                    <jats:styled-content style=\"fixed-case\">ASIA<\/jats:styled-content>\n                    . This case suggests that silicone leakage after implant rupture, rather than the duration of exposure, is a critical factor in disease development and progression. The sarcoid\u2010like pulmonary lesions in this case may represent a sarcoid\u2010like granulomatous reaction triggered by silicone exposure in the setting of\n                    <jats:styled-content style=\"fixed-case\">ASIA<\/jats:styled-content>\n                    , rather than true systemic sarcoidosis. Early implant removal appears beneficial for both the diagnosis and treatment of\n                    <jats:styled-content style=\"fixed-case\">ASIA<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70497","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T05:54:20Z","timestamp":1770098060000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Autoimmune\/Inflammatory Syndrome Induced by Adjuvants With Sarcoid\u2010Like Pulmonary Lesions Triggered by Silicone Implant Rupture and Improved After Explantation"],"prefix":"10.1002","volume":"14","author":[{"given":"Yuki","family":"Tsuda","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0854-3494","authenticated-orcid":false,"given":"Ryota","family":"Kikuchi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nao","family":"Shioiri","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daigo","family":"Imasato","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waku","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taro","family":"Kufukihara","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Kogami","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuta","family":"Kono","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Medical University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2010.07.003"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10101436"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyy217"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000155145.60670.e4"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-017-3748-9"},{"issue":"10","key":"e_1_2_11_7_1","first-page":"2263","article-title":"Rupture of Silicone Breast Implants and Systemic Symptoms: A Comparative Study","volume":"30","author":"Vermeulen R. C.","year":"2003","journal-title":"Journal of Rheumatology"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70497","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70497","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70497","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T07:23:26Z","timestamp":1773386606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/rcr2.70497"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70497","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70497"}}