{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T05:56:53Z","timestamp":1774591013593,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Sodium\u2010glucose cotransporter 2 inhibitors (SGLT2i) also called\n                    <jats:italic>flozins<\/jats:italic>\n                    or\n                    <jats:italic>gliflozins<\/jats:italic>\n                    have been demonstrated to have multi\u2010system benefits across the endocrine, metabolic, renal and cardiovascular systems. As a result, indications for use of SGLT2i have grown, however, there is limited evidence describing their use in people with CF (pwCF). We describe safe, tolerable and effective use of SGLT2i in three adults with CF. Indications for SGLT2i in our three cases varied. Our first case required it for glycaemic management due to predominantly type 2 diabetes phenotype. The next case had heavy proteinuria due to CF diabetes\u2010related nephropathy. And the last case had non\u2010diabetes related nephropathy. All cases tolerated SGLT2i without any side effects. Our findings add to the limited literature on SGLT2i use in pwCF, which will become increasingly relevant given an ageing CF population in the post\u2010modulator era.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70533","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T15:05:01Z","timestamp":1773327901000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sodium Glucose\u2010Like Co\u2010Transporter 2 Inhibitor (\n                    <scp>SGLT2i<\/scp>\n                    ) Use in Adults With Cystic Fibrosis"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6236-3876","authenticated-orcid":false,"given":"Ellie","family":"Johnson","sequence":"first","affiliation":[{"name":"The Prince Charles Hospital, Adult Cystic Fibrosis Centre  Brisbane Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8553-4786","authenticated-orcid":false,"given":"Angela","family":"Matson","sequence":"additional","affiliation":[{"name":"The Prince Charles Hospital, Adult Cystic Fibrosis Centre  Brisbane Australia"},{"name":"Dept Nutrition &amp; Dietetics Allied Health, the Prince Charles Hospital, Adult Cystic Fibrosis Centre  Brisbane Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robyn","family":"Cobb","sequence":"additional","affiliation":[{"name":"The Prince Charles Hospital, Adult Cystic Fibrosis Centre  Brisbane Australia"},{"name":"Dept Physiotherapy Allied Health the Prince Charles Hospital  Chermside Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5456-2699","authenticated-orcid":false,"given":"Shanal","family":"Kumar","sequence":"additional","affiliation":[{"name":"The Prince Charles Hospital, Adult Cystic Fibrosis Centre  Brisbane Australia"},{"name":"Senior Lecturer, University of Queensland  St Lucia Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1479164114561992"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2022.109927"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc25-S009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/ANNALS-24-01926"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja2.51656"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcte.2025.100403"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.2025.211.Abstracts.A1729"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab818"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.70104"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70533","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70533","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70533","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T04:17:09Z","timestamp":1774585029000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/rcr2.70533"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70533","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70533"}}