{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T09:01:23Z","timestamp":1781254883884,"version":"3.54.1"},"reference-count":3,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Accurate mediastinal staging is critical in lung cancer, particularly when involvement of specific nodal stations determines curative intent. Sampling high mediastinal lymph nodes adjacent to major vascular structures presents technical and safety challenges, especially when conventional endobronchial ultrasound approaches are unsuitable. We report a case of contrast\u2010enhanced cone\u2010beam computed tomography (CBCT)\u2010guided robotic bronchoscopic biopsy of a high mediastinal lymph node adjacent to major vessels. Intravenous contrast during CBCT acquisition enabled clear differentiation between the target node and adjacent vascular structures, facilitating accurate segmentation, safe navigation and confirmation of tool\u2013target contact prior to sampling. This case highlights the feasibility and role of intravenous contrast in CBCT\u2010guided bronchoscopy to improve procedural confidence and safety during complex mediastinal biopsies.<\/jats:p>","DOI":"10.1002\/rcr2.70581","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T04:45:16Z","timestamp":1775709916000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Contrast\u2010Enhanced Cone\u2010Beam\n                    <scp>CT<\/scp>\n                    \u2010Guided Robotic Bronchoscopic Biopsy of a Mediastinal Lymph Node Adjacent to Major Vascular Structures"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1431-8724","authenticated-orcid":false,"given":"Tajalli","family":"Saghaie","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Health and Human Sciences Macquarie University  Sydney Australia"},{"name":"Concord Repatriation General Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1102-6081","authenticated-orcid":false,"given":"Miriam","family":"Boxer","sequence":"additional","affiliation":[{"name":"Concord Repatriation General Hospital  Sydney Australia"},{"name":"Icon Cancer Care  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Linton","sequence":"additional","affiliation":[{"name":"Concord Repatriation General Hospital  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedram","family":"Mohammadieh","sequence":"additional","affiliation":[{"name":"Macquarie University Health  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Warnecke","sequence":"additional","affiliation":[{"name":"Macquarie University Health  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Mortimer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Health and Human Sciences Macquarie University  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd\u201024\u20101224"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm14228009"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.14778"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70581","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70581","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70581","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T08:55:20Z","timestamp":1781254520000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/rcr2.70581"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70581","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2026-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70581"}}