{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T03:03:21Z","timestamp":1779937401609,"version":"3.53.1"},"reference-count":5,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Malignant pleural disease is a clinical condition of growing health importance, often presenting as pleural thickening and\/or malignant pleural effusion. Rapid and accurate diagnosis is crucial to guide treatment decisions. In most cases, pleural biopsy is necessary: thoracoscopy, ultrasound\u2010 and CT\u2010guided biopsies all offer high accuracy and good safety. The use of ultrasound has revolutionised procedural approaches, increasing safety thanks to its good sensitivity and very high specificity, allowing direct and immediate visualisation of complications such as pneumothorax or haemorrhage. In this case report, we describe how intrapleural adrenaline instillation successfully controlled pleural haemorrhage, which was identified as a complication of ultrasound\u2010guided pleural biopsy thanks to real\u2010time ultrasound and colour Doppler monitoring of the procedure. Adrenaline was administered under ultrasound guidance directly into the vascular structure presumed to be the source of the bleeding. This technique can be considered an effective and minimally invasive approach for managing bleeding complications of ultrasound\u2010guided pleural biopsy, even though larger studies are needed to validate efficacy and safety of this approach.<\/jats:p>","DOI":"10.1002\/rcr2.70595","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:27:09Z","timestamp":1779164829000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["No Time to Bleed! Ultrasound\u2010Guided Management of a Pleural Biopsy Complication: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4784-1950","authenticated-orcid":false,"given":"Daniel","family":"Piamonti","sequence":"first","affiliation":[{"name":"Department of Clinical, Internal, Anesthesiologic and Cardiovascular Sciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3105-2841","authenticated-orcid":false,"given":"Francesca","family":"Stirpe","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Respiratory Sciences, S Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9876-8074","authenticated-orcid":false,"given":"Noemi","family":"Calabr\u00f2","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Respiratory Sciences, S Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erminio","family":"Carriero","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Respiratory Sciences, S Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Romaniello","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Respiratory Sciences, S Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Sglavo","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Respiratory Sciences, S Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Giarnieri","sequence":"additional","affiliation":[{"name":"Cytopathology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Carico","sequence":"additional","affiliation":[{"name":"Cytopathology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2265-7455","authenticated-orcid":false,"given":"Pasquale","family":"Pignatelli","sequence":"additional","affiliation":[{"name":"Department of Clinical, Internal, Anesthesiologic and Cardiovascular Sciences Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3042-0765","authenticated-orcid":false,"given":"Matteo","family":"Bonini","sequence":"additional","affiliation":[{"name":"Department of Public Health and Infectious Diseases Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Ricci","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Respiratory Sciences, S Andrea Hospital Sapienza University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201807-1415ST"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000511626"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2024.02.041"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2022-219784"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2025.04.010"}],"container-title":["Respirology Case 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