{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T03:03:22Z","timestamp":1779937402503,"version":"3.53.1"},"reference-count":5,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Rheumatoid arthritis (RA) is an autoimmune disease where immunological activation often precedes clinical onset. Although respiratory infections are recognized risk factors for RA, the onset of RA shortly after acute infection remains poorly characterized. Herein, we report a rare case of seropositive RA that became clinically apparent during the acute phase of lung infection. An 87\u2010year\u2010old man who had never smoked was diagnosed with a lung abscess caused by methicillin\u2010susceptible\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    <\/jats:styled-content>\n                    . Post discharge, he developed polyarthritis, and laboratory tests revealed positive results for rheumatoid factor (RF) and anti\u2010citrullinated protein antibodies (ACPA). He was diagnosed with seropositive RA, and his symptoms improved with corticosteroid therapy. Retrospective review of positron emission tomography scans performed before admission revealed inflammatory uptake in multiple joints, suggesting a preclinical phase. This case suggests that acute respiratory infection may accelerate the transition from latent autoimmunity to clinically overt RA, highlighting the diagnostic value of RF and ACPA testing in new\u2010onset arthritis after infection.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70602","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:28:28Z","timestamp":1777447708000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Seropositive Rheumatoid Arthritis Emerging During Acute Phase of Lung Abscess: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Yusuke","family":"Arai","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Sano Kosei General Hospital  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5299-3978","authenticated-orcid":false,"given":"Hiromu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sano Kosei General Hospital  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuoto","family":"Hiramoto","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine Keio University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aina","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sano Kosei General Hospital  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Asami","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sano Kosei General Hospital  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Sano Kosei General Hospital  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-018-0070-0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2021.11.008"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00064014"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-1977-9"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-200990"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70602","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70602","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T02:29:33Z","timestamp":1779935373000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,29]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/rcr2.70602"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70602","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,29]]},"assertion":[{"value":"2026-02-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70602"}}