{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:58:55Z","timestamp":1785383935705,"version":"3.55.0"},"reference-count":8,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Pulmonary nocardiosis may occur in immunocompetent patients with structural lung disease and may resemble the progression of nontuberculous mycobacterial pulmonary disease. We report an 81\u2010year\u2010old immunocompetent woman with chronic bronchiectasis and prior\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Mycobacterium kansasii<\/jats:italic>\n                    <\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>M. intracellulare<\/jats:italic>\n                    <\/jats:styled-content>\n                    , and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>M. abscessus<\/jats:italic>\n                    <\/jats:styled-content>\n                    infections. Despite persistently negative sputum mycobacterial cultures, chest computed tomography (CT) revealed progressive nodular bronchiectatic changes. Bronchial washing from the right B5 bronchus yielded\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Nocardia cyriacigeorgica<\/jats:italic>\n                    <\/jats:styled-content>\n                    ; mycobacterial studies were negative. Trimethoprim\u2013sulfamethoxazole was stopped shortly after initiation because of drug eruption, and minocycline monotherapy led to transient symptomatic and radiologic improvement. However, follow\u2010up CT at 6\u2009months revealed radiologic progression. Repeat bronchoscopy was culture\u2010negative, but bronchial washing cytology revealed filamentous organisms suggestive of persistent nocardial infection. Minocycline monotherapy was continued for 12\u2009months. Chest CT at 12\u2009months revealed new contralateral left upper lobe bronchocentric abnormalities. This case highlights the importance of bronchial washing and longitudinal reassessment when radiologic progression remains unexplained by sputum evaluation.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70654","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T03:37:46Z","timestamp":1784518666000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Nocardia cyriacigeorgica<\/i>\n                    Identified by Bronchial Washing During Evaluation of Radiologic Progression in a Patient With Prior Nontuberculous Mycobacterial Diseases"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9781-258X","authenticated-orcid":false,"given":"Hidenori","family":"Takahashi","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Shinagawa Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanako","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Shinagawa Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yugo","family":"Satake","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Shinagawa Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsuko","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Pathology Tokyo Shinagawa Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Shinagawa Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaharu","family":"Shinkai","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokyo Shinagawa Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2016.08.004"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2024.107922"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/rcr2.1036"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2023-256007"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11547-009-0479-2"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24916"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-95870-2"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.12.019"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70654","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70654","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:06:38Z","timestamp":1785380798000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/rcr2.70654"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70654","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70654"}}