{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:58:24Z","timestamp":1785383904907,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Congenital drug\u2010resistant tuberculosis (DR\u2010TB) is a rare condition with no standardized treatment. Congenital TB itself is a life\u2010threatening condition. The clinical manifestations can be nonspecific, particularly in preterm infants, which can further reduce diagnostic awareness. We report a case of a 32\u2010week preterm baby with rifampicin\u2010resistant TB. She was born with respiratory distress and early\u2010onset jaundice, initially suspected of sepsis and admitted to the NICU. The infant initially showed clinical improvement at 3\u2009days of life, but at 23\u2009days of life, the clinical condition worsened despite a sterile blood culture. The mother was subsequently diagnosed with miliary TB with rifampicin\u2010resistant Xpert sputum. The infant's gastric lavage Xpert MTB\/RIF confirmed rifampicin\u2010resistant TB. At 32\u2009days of life, she received a five\u2010drug regimen, including bedaquiline. She completed 12\u2009months of treatment with a favourable outcome. This case highlights the challenges of early recognition and treatment selection in congenital DR\u2010TB.<\/jats:p>","DOI":"10.1002\/rcr2.70680","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T04:39:08Z","timestamp":1784608748000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The First Documented Case of Congenital Drug\u2010Resistant Tuberculosis in Indonesia: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2034-8046","authenticated-orcid":false,"given":"Cynthia","family":"Centauri","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Indonesia \u2010 Universitas Indonesia Hospital  Depok Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srisadono Fauzi","family":"Adiprabowo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Indonesia \u2010 Universitas Indonesia Hospital  Depok Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5680-6244","authenticated-orcid":false,"given":"Putri Maharani Tristanita","family":"Marsubrin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Indonesia \u2010 Universitas Indonesia Hospital  Depok Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0826-3967","authenticated-orcid":false,"given":"Irandi Putra","family":"Pratomo","sequence":"additional","affiliation":[{"name":"Department of Pulmonology University of Indonesia \u2010 Universitas Indonesia Hospital  Depok Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Global Tuberculosis Report 2025","author":"World Health Organization","year":"2025"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1239734"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciad540"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmy020"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/ftubr.2024.1343217"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70680","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70680","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:04:52Z","timestamp":1785380692000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/rcr2.70680"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70680","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2025-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70680"}}