{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:18:17Z","timestamp":1787804297034,"version":"build-2784847793"},"reference-count":6,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Respiratory syncytial virus (RSV) causes significant morbidity in immunocompromised adults. We describe a post\u2010operative bilateral lung transplant recipient with donor\u2010derived RSV who developed increasing viral load and progressive respiratory failure despite conventional therapy (enteral ribavirin, methylprednisolone, IVIG) and was ultimately administered palivizumab. By day 42, the patient remained ventilator\u2010dependent with low RSV PCR cycle threshold (Ct) values on bronchoalveolar lavage. Transbronchial biopsies showed mixed inflammatory appearances, indicating either acute RSV infection or possible rejection. Following administration of single dose intramuscular palivizumab (10\u2009mg\/kg) we observed an improving clinical trajectory and increasing Ct values. RSV became undetectable by day 64, with follow\u2010up biopsies revealing no rejection. The patient was successfully discharged on day 87 and continues to show stable allograft function. This case demonstrates safe use of single dose palivizumab to augment conventional therapy for life\u2010threatening RSV in the profoundly immunocompromised lung transplant recipient.<\/jats:p>","DOI":"10.1002\/rcr2.70706","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:04:03Z","timestamp":1785384243000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Palivizumab for Donor\u2010Derived\n                    <scp>RSV<\/scp>\n                    Infection in an Adult Bilateral Lung Transplant Recipient: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2409-5925","authenticated-orcid":false,"given":"Rosemary","family":"Meharry","sequence":"first","affiliation":[{"name":"Western General Hospital  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9726-8382","authenticated-orcid":false,"given":"Cassandra","family":"Vale","sequence":"additional","affiliation":[{"name":"The Prince Charles Hospital Intensive Care Unit  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5254-4144","authenticated-orcid":false,"given":"John","family":"Mackintosh","sequence":"additional","affiliation":[{"name":"The Prince Charles Hospital Queensland Lung Transplant Service  Brisbane Australia"},{"name":"Faculty of Medicine University of Queensland  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"issue":"5","key":"e_1_2_11_2_1","first-page":"1789","article-title":"Burden, Epidemiology, and Outcomes of Microbiologically Confirmed Respiratory Viral Infections in Solid Organ Transplant Recipients: A Nationwide, Multi\u2010Season Prospective Cohort Study am J Transplant","volume":"21","author":"Mombelli M.","year":"2021","journal-title":"Clinical Microbiology and Infection"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/jeccm-22-59"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/723407"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(25)00093-8"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.07.050"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2009.00453.x"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70706","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70706","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70706","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:23:43Z","timestamp":1787801023000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,29]]},"references-count":6,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/rcr2.70706"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70706","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,29]]},"assertion":[{"value":"2026-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70706"}}