{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:18:14Z","timestamp":1787804294763,"version":"build-2784847793"},"reference-count":6,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    A 4\u2010year\u2010old girl with no prior respiratory history developed refractory intraoperative hypoxemia during elective dental surgery under general anaesthesia. Despite 100% inspired oxygen and systematic exclusion of all conventional causes of desaturation, pulse oximetry (SpO\n                    <jats:sub>2<\/jats:sub>\n                    ) failed to exceed 94%. Postoperative contrast\u2010enhanced chest computed tomography identified a 2.01\u2010cm pulmonary arteriovenous malformation (PAVM) in the right lung, and subsequent molecular genetic testing confirmed hereditary hemorrhagic telangiectasia (HHT). The patient was discharged with baseline SpO\n                    <jats:sub>2<\/jats:sub>\n                    of 85%\u201395% on room air and established on long\u2010term paediatric pulmonary follow\u2010up. This case highlights that PAVMs associated with HHT can manifest as unexplained perioperative hypoxemia in asymptomatic children, and that general anaesthesia with positive pressure ventilation may unmask previously compensated right\u2010to\u2010left shunting. Early recognition enables appropriate perioperative management and timely HHT surveillance.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70707","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T03:19:58Z","timestamp":1786591198000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidental Diagnosis of Hereditary Hemorrhagic Telangiectasia Following Perioperative Hypoxemia in a 4\u2010Year\u2010Old Child"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2496-8378","authenticated-orcid":false,"given":"Chun\u2010Chen","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Taoyuan Armed Forces General Hospital  Taoyuan Taiwan"},{"name":"School of Medicine National Defense Medical University  Taipei Taiwan"},{"name":"Department of Anesthesiology Kaohsiung Veterans General Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8948-6603","authenticated-orcid":false,"given":"Chen\u2010Hsiu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Kaohsiung Veterans General Hospital  Kaohsiung Taiwan"},{"name":"School of Medicine National Yang Ming Chiao Tung University  Taipei Taiwan"},{"name":"National Sun Yat\u2010Sen University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199510053331407"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.087452"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/joacp.JOACP_181_18"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/85.3.440"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-013-1601-0"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-1949"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70707","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.70707","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.70707","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T03:23:45Z","timestamp":1787801025000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.70707"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":6,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/rcr2.70707"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.70707","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"value":"2051-3380","type":"print"},{"value":"2051-3380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70707"}}