{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:18:13Z","timestamp":1787804293589,"version":"build-2784847793"},"reference-count":7,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Reduced digital perfusion associated with Raynaud phenomenon may cause spuriously low fingertip pulse oximetry readings during the 6\u2010minute walk test (6MWT), potentially leading to overestimation of exercise\u2010induced hypoxaemia in patients with interstitial lung disease. We report a 39\u2010year\u2010old woman with non\u2010specific interstitial pneumonia and Raynaud phenomenon who underwent repeated 6MWTs. Fingertip SpO\n                    <jats:sub>2<\/jats:sub>\n                    progressively decreased from 96% to 82%, whereas forehead SpO\n                    <jats:sub>2<\/jats:sub>\n                    remained stable (93%\u201398%). Simultaneously, transcutaneous oxygen tension (TcPO\n                    <jats:sub>2<\/jats:sub>\n                    ) measured on the volar forearm remained unchanged. Progressive finger cooling and digital pallor were also observed. Fingertip SpO\n                    <jats:sub>2<\/jats:sub>\n                    rapidly returned to baseline during recovery. These findings suggested that the apparent desaturation reflected reduced digital perfusion rather than true systemic hypoxaemia. This case highlights the potential limitations of fingertip pulse oximetry during exercise in patients with Raynaud phenomenon. Alternative methods of assessing oxygenation, such as forehead pulse oximetry or TcPO\n                    <jats:sub>2<\/jats:sub>\n                    , may be useful during the 6MWT when fingertip SpO\n                    <jats:sub>2<\/jats:sub>\n                    readings are discordant with the clinical presentation.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70737","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:07:02Z","timestamp":1787645222000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spurious Fingertip Oxygen Desaturation During the 6\u2010Minute Walk Test in a Patient With\n                    <scp>NSIP<\/scp>\n                    and Raynaud Phenomenon: The Value of Forehead Pulse Oximetry and Transcutaneous Oxygen Tension"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5288-5750","authenticated-orcid":false,"given":"Yusuke","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1675-1740","authenticated-orcid":false,"given":"Masayoshi","family":"Takamori","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honoka","family":"Sunaga","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Natsume","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuto","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiko","family":"Tsukada","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azusa","family":"Tsukada","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiko","family":"Uchida","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nana","family":"Yazawa","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Hoshi","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"},{"name":"Respiratory Endoscopy Center Dokkyo Medical University Hospital  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9480-5923","authenticated-orcid":false,"given":"Seiji","family":"Niho","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Clinical Immunology Dokkyo Medical University School of Medicine  Mibu Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00150314"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202009-3608ST"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2012.96"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/14799731211070844"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00298.2010"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2012.02133.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-024-05532-5"}],"container-title":["Respirology Case 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