{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:00:36Z","timestamp":1790301636182,"version":"4.1.0"},"reference-count":5,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acute exacerbation of interstitial lung disease (AE\u2010ILD) is often idiopathic, although viral infections are recognized precipitating factors. We report an adult patient with underlying ILD who developed acute respiratory deterioration in the setting of primary parvovirus B19 infection. A 70\u2010year\u2010old Japanese man was admitted to our department with a low\u2010grade fever and a facial rash. Two years prior to admission, the patient had been diagnosed with ILD, which had been treated with systemic corticosteroids that were subsequently discontinued following clinical improvement. High\u2010resolution computed tomography (HRCT) revealed newly developed bilateral ground\u2010glass opacities. Infection with parvovirus B19 was confirmed by serological testing and bronchoalveolar lavage results. Although the precise contribution of parvovirus B19\u2010associated lung injury, infection\u2010triggered AE\u2010ILD and acute exacerbation of the underlying ILD could not be definitively determined, steroid pulse therapy led to clinical and radiological improvement. This case highlights the importance of considering parvovirus B19 infection as a potential contributor to acute respiratory deterioration in patients with underlying ILD.<\/jats:p>","DOI":"10.1002\/rcr2.70751","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:05:27Z","timestamp":1788249927000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Respiratory Deterioration Following Parvovirus\n                    <scp>B19<\/scp>\n                    Infection in a Patient With Interstitial Lung Disease: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7282-205X","authenticated-orcid":false,"given":"Tomoki","family":"Kishaba","sequence":"first","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0524-0508","authenticated-orcid":false,"given":"Satoshi","family":"Marumo","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuya","family":"Nishida","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eri","family":"Nohara","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jukiya","family":"Higashi","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiaki","family":"Okura","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiori","family":"Jinno","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Tashima","sequence":"additional","affiliation":[{"name":"Department of Respirology Kitano Hospital, The Tazuke Kofukai Medical Research Institute  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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2018.02.003"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201604\u20100801CI"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2696\u201019"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.3.485\u2010505.2002"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068393"}],"container-title":["Respirology Case 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