{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:53:46Z","timestamp":1790913226612,"version":"4.1.0"},"reference-count":11,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Bronchiectasis in ANCA\u2010associated vasculitis (AAV) is usually attributed to structural damage from established disease. We report a 74\u2010year\u2010old woman with 7\u2009years of culture\u2010negative bronchiectasis, incompletely responsive to corticosteroids, in whom AAV was diagnosed after she developed palpable purpura, haemoptysis, hematuria and acute kidney injury. MPO\u2010ANCA was markedly elevated (250.2\u2009U\/mL; reference &lt;\u20091.0\u2009U\/mL) with PR3\u2010ANCA negative. Renal biopsy showed pauci\u2010immune crescentic glomerulonephritis, Berden focal class (one of 14 glomeruli with a cellular crescent). Induction with intravenous methylprednisolone and rituximab produced substantial renal recovery (eGFR nadir 23, stabilizing at 60\u2009mL\/min\/1.73\u2009m\n                    <jats:sup>2<\/jats:sup>\n                    at 15\u2009months) and near\u2010complete resolution of the pulmonary consolidations. This case describes an airway\u2010first AAV phenotype. She met none of the trigger features that current guidelines use to prompt autoimmune screening, identifying a diagnostic blind spot in progressive culture\u2010negative bronchiectasis without systemic features.\n                  <\/jats:p>","DOI":"10.1002\/rcr2.70777","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:02:30Z","timestamp":1790910150000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bronchiectasis as the Sentinel Manifestation of\n                    <scp>ANCA<\/scp>\n                    \u2010Associated Vasculitis: A Case Report and Literature Review"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4799-6878","authenticated-orcid":false,"given":"Andrew","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Kaiser Permanente Los Angeles Medical Center  Los Angeles California 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6384-5938","authenticated-orcid":false,"given":"Brannen","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Kaiser Permanente Los Angeles Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010050477"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41983"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.46497\/ArchRheumatol.2024.10352"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2017.12.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.190313"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00311-2025"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01126-2025"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2026.06.057"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24634"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41982"}],"container-title":["Respirology 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