{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:58:12Z","timestamp":1764403092286,"version":"3.41.2"},"reference-count":6,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T00:00:00Z","timestamp":1624406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We herein report a case of allergic bronchopulmonary aspergillosis (ABPA) that occurred in a man treated with adalimumab for ankylosing spondylitis (AS). A 69\u2010year\u2010old man with a history of ankylosing spondylitis treated by adalimumab, an anti\u2010tumour necrosis factor\u2010\u03b1 (TNF\u2010\u03b1) antibody, developed cough and wheezing. Chest computed tomography showed obstruction of dilated left upper lobe bronchus by high attenuation mucus as well as central bronchiectasis. Both <jats:italic>Aspergillus<\/jats:italic>\u2010specific immunoglobulin E (IgE) and <jats:italic>Aspergillus<\/jats:italic> precipitating antibody were positive and <jats:italic>Aspergillus fumigatus<\/jats:italic> was detected in a sputum culture. According to the new diagnostic criteria, the patient was diagnosed with ABPA. His condition rapidly improved after the withdrawal of adalimumab and initiation of prednisolone and itraconazole. Anti\u2010TNF\u2010\u03b1 antibody might cause ABPA through both aggravation of the host's T\u2010helper 2 immunological response and anti\u2010fungal response.<\/jats:p>","DOI":"10.1002\/rcr2.805","type":"journal-article","created":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T05:09:02Z","timestamp":1624511342000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Allergic bronchopulmonary aspergillosis in a patient with ankylosing spondylitis treated with adalimumab"],"prefix":"10.1002","volume":"9","author":[{"given":"Yudai","family":"Suzuki","sequence":"first","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3016-233X","authenticated-orcid":false,"given":"Naoki","family":"Takasaka","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2291-2137","authenticated-orcid":false,"given":"Sachi","family":"Matsubayashi","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayako","family":"Kojima","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyota","family":"Shinfuku","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masami","family":"Yamada","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikumi","family":"Fujisaki","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Seki","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Seki","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Ishikawa","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuyoshi","family":"Kuwano","sequence":"additional","affiliation":[{"name":"Division of Respiratory Diseases, Department of Internal Medicine The Jikei University Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,23]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.08.029"},{"key":"e_1_2_4_3_1","first-page":"315","article-title":"Counter\u2010regulatory balance: atopic dermatitis in patients undergoing infliximab infusion therapy","volume":"3","author":"Chan JL","year":"2004","journal-title":"J. Drugs Dermatol."},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh412"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2785-19"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.2177\/jsci.39.84"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12354"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.805","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.805","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.805","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:19:52Z","timestamp":1693354792000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.805"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,23]]},"references-count":6,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/rcr2.805"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.805","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2021,6,23]]},"assertion":[{"value":"2021-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00805"}}